DHA-Enriched Phospholipids Exhibit Anti-Depressant Effects by Immune and Neuroendocrine Regulation in Mice: A Study on Dose- and Structure-Activity Relationship.

Cheng-Cheng WangJun-Yi WangHao-Hao ShiYing-Cai ZhaoJin-Yue YangYu-Ming WangTeruyoshi YanagitaChang-Hu XueTian-Tian Zhang

Published in: Molecular nutrition & food research (2022)

The limited effect of DHA on depression is remedied by chemical structure adjustment to DHA-PL and three-fold dose. The present findings provide a potential novel candidate or targeted dietary patterns to prevent and treat depression.

Keyphrases

fatty acid
structure activity relationship
depressive symptoms
sleep quality
cancer therapy
high fat diet induced
type diabetes
drug delivery
skeletal muscle
risk assessment
wild type