Serum neurofilament light for detecting disease activity in individual patients in multiple sclerosis: A 48-week prospective single-center study.
Magnus JohnssonY T StenbergH H FarmanK BlennowH ZetterbergC MalmeströmSofia SandgrenIgal RosensteinJan N LyckeM AxelssonLenka NovakovaPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2024)
One out of five patients with relapse and/or CELs did not change significantly in post-baseline sNfL levels. The utility of repeated sNfL measurements to monitor disease activity is complementary rather than a substitute for clinical and MRI measures.
Keyphrases
- disease activity
- systemic lupus erythematosus
- rheumatoid arthritis
- rheumatoid arthritis patients
- ankylosing spondylitis
- multiple sclerosis
- juvenile idiopathic arthritis
- end stage renal disease
- ejection fraction
- newly diagnosed
- magnetic resonance imaging
- randomized controlled trial
- contrast enhanced
- cerebrospinal fluid
- computed tomography
- patient reported outcomes
- magnetic resonance
- patient reported
- study protocol
- white matter