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Differential effects of single fatty acids and fatty acid mixtures on the phosphoinositide 3-kinase/Akt/eNOS pathway in endothelial cells.

Kim G JacksonKatie J NewensMichael J FryAbby K ThompsonChristine M Williams
Published in: European journal of nutrition (2022)
Our findings provide novel insights into the modulation of the PI3K/Akt/eNOS pathway by single fatty acids and fatty acid mixtures. In particular, OA appears to promote signalling via this pathway, with further work required to determine the primary molecular site(s) of action.
Keyphrases
  • fatty acid
  • endothelial cells
  • ionic liquid
  • pi k akt
  • signaling pathway
  • nitric oxide synthase
  • cell proliferation
  • high glucose
  • nitric oxide
  • knee osteoarthritis
  • vascular endothelial growth factor