Application of Clinical Decision Support System to Assist Breast Cancer Patients with Lifestyle Modifications during the COVID-19 Pandemic: A Randomised Controlled Trial.
Panos PapandreouAristea GioxariFrantzeska NimeeMaria SkouroliakouPublished in: Nutrients (2021)
Clinical decision support systems (CDSS) are data aggregation tools based on computer technology that assist clinicians to promote healthy weight management and prevention of cardiovascular diseases. We carried out a randomised controlled 3-month trial to implement lifestyle modifications in breast cancer (BC) patients by means of CDSS during the COVID-19 pandemic. In total, 55 BC women at stages I-IIIA were enrolled. They were randomly assigned either to Control group, receiving general lifestyle advice (n = 28) or the CDSS group (n = 27), to whom the CDSS provided personalised dietary plans based on the Mediterranean diet (MD) together with physical activity guidelines. Food data, anthropometry, blood markers and quality of life were evaluated. At 3 months, higher adherence to MD was recorded in the CDSS group, accompanied by lower body weight (kg) and body fat mass percentage compared to control (p < 0.001). In the CDSS arm, global health/quality of life was significantly improved at the trial endpoint (p < 0.05). Fasting blood glucose and lipid levels (i.e., cholesterol, LDL, triacylglycerols) of the CDSS arm remained unchanged (p > 0.05) but were elevated in the control arm at 3 months (p < 0.05). In conclusion, CDSS could be a promising tool to assist BC patients with lifestyle modifications during the COVID-19 pandemic.
Keyphrases
- clinical decision support
- physical activity
- electronic health record
- blood glucose
- cardiovascular disease
- weight loss
- body weight
- metabolic syndrome
- global health
- study protocol
- end stage renal disease
- body mass index
- clinical trial
- glycemic control
- molecular dynamics
- chronic kidney disease
- type diabetes
- deep learning
- ejection fraction
- polycystic ovary syndrome
- peritoneal dialysis
- randomized controlled trial
- risk assessment
- prognostic factors
- pregnant women
- skeletal muscle
- adipose tissue
- sleep quality
- pregnancy outcomes
- artificial intelligence
- blood pressure