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Building an integrated serosurveillance platform to inform public health interventions: Insights from an experts' meeting on serum biomarkers.

Kirsten E WiensBarbara JaureguiBenjamin F ArnoldKathryn BankeDjibril WadeKyla HayfordAdriana Costero-Saint DenisRobert H HallHenrik SaljeIsabel Rodriguez-BarraquerAndrew S AzmanGuy VernetDaniel T Leungnull null
Published in: PLoS neglected tropical diseases (2022)
The use of biomarkers to measure immune responses in serum is crucial for understanding population-level exposure and susceptibility to human pathogens. Advances in sample collection, multiplex testing, and computational modeling are transforming serosurveillance into a powerful tool for public health program design and response to infectious threats. In July 2018, 70 scientists from 16 countries met to perform a landscape analysis of approaches that support an integrated serosurveillance platform, including the consideration of issues for successful implementation. Here, we summarize the group's insights and proposed roadmap for implementation, including objectives, technical requirements, ethical issues, logistical considerations, and monitoring and evaluation.
Keyphrases
  • public health
  • quality improvement
  • high throughput
  • immune response
  • primary care
  • healthcare
  • endothelial cells
  • global health
  • physical activity
  • toll like receptor
  • pluripotent stem cells
  • gram negative
  • dendritic cells