Genetic risk scores: are they important for diabetes management? results from multiple cross-sectional studies.

Sureka Nagarajah Abdullah Alkandari Pedro-Manuel Marques-Vidal

Published in: Diabetology & metabolic syndrome (2023)

In this study, we confirmed the association between most published GRS and diabetes. Conversely, no consistent association between GRS and diabetes control was found. Use of GRS to manage patients with T2DM in clinical practice is not justified.

Keyphrases

type diabetes
glycemic control
cardiovascular disease
cross sectional
clinical practice
randomized controlled trial
metabolic syndrome
gene expression
skeletal muscle
meta analyses