Effect of Lampaya medicinalis Phil. (Verbenaceae) and Palmitic Acid on Insulin Signaling and Inflammatory Marker Expression in Human Adipocytes.
Gabriela YuriMariana CifuentesPedro CisternasAdrián ParedesPaulina OrmazabalPublished in: Pharmaceuticals (Basel, Switzerland) (2024)
Our results suggest a beneficial effect of HEL by improving PA-induced impairment on molecular markers of insulin signaling, glucose uptake and inflammation in adipocytes. Further studies are necessary to elucidate whether lampaya may constitute a preventive strategy for people whose circulating PA levels contribute to IR and inflammation during aging and obesity.
Keyphrases
- type diabetes
- oxidative stress
- adipose tissue
- high fat diet induced
- diabetic rats
- endothelial cells
- insulin resistance
- glycemic control
- poor prognosis
- high glucose
- metabolic syndrome
- weight loss
- induced pluripotent stem cells
- blood pressure
- body mass index
- case control
- binding protein
- pluripotent stem cells
- long non coding rna