The Efficacy and Safety of the Chinese Herbal Formula, JTTZ, for the Treatment of Type 2 Diabetes with Obesity and Hyperlipidemia: A Multicenter Randomized, Positive-Controlled, Open-Label Clinical Trial.
Xiaotong YuLipeng XuQiang ZhouShengping WuJiaxing TianChunli PiaoHailong GuoJun ZhangLiping LiShentao WuMeizhen GuoYuzhi HongWeirong PuXiyan ZhaoYang LiuBing PangZhiping PengSong WangFengmei LianXiaolin TongPublished in: International journal of endocrinology (2018)
The JTTZ formula led to safe and significant improvements in the blood glucose, blood lipids, and weight levels; relieved symptoms; and enhanced β cell function for T2D patients with obesity and hyperlipidemia. The JTTZ formula has shown that it could potentially be developed as an alternative medicine for patients with T2D, particularly those who cannot tolerate metformin or other hypoglycemic drugs. This trial was registered with Clinicaltrials.gov NCT01471275.
Keyphrases
- open label
- phase iii
- phase ii
- clinical trial
- blood glucose
- high fat diet induced
- weight loss
- double blind
- insulin resistance
- weight gain
- study protocol
- human milk
- metabolic syndrome
- high fat diet
- placebo controlled
- glycemic control
- phase ii study
- type diabetes
- body mass index
- skeletal muscle
- randomized controlled trial
- blood pressure
- low birth weight
- physical activity
- sleep quality
- squamous cell carcinoma
- fatty acid
- depressive symptoms
- body weight
- preterm birth