Longitudinal analysis of aqueous humour cytokine expression and OCT-based imaging biomarkers in retinal vein occlusions treated with anti-vascular endothelial growth factor therapy in the IMAGINE study.
Sruthi ArepalliCharles C WykoffJoseph R AbrahamLeina LunascoHannah YuMing HuSunil K SrivastavaJamie L ReeseDavid BrownJustis P EhlersPublished in: Eye (London, England) (2022)
Cytokine expression was linked to specific OCT features and treatment response in RVO. Identification of an imaging phenotype that could serve as a surrogate for underlying active disease pathways could enhance treatment decision-making and precision medicine.