Age, Sex, and Depot-Specific Differences in Adipose-Tissue Estrogen Receptors in Individuals with Obesity.

Jay W PorterJillian L BarnasRebecca WellyNicole SpencerJames PittVictoria J Vieira-PotterJill A Kanaley

Published in: Obesity (Silver Spring, Md.) (2020)

In morbid obesity, sex and age affect AT ERs, lipid metabolism, mitochondrial uncoupling protein 1, and inflammatory expression in an AT depot-dependent manner. The SQAT immunometabolic profile is heavily influenced by age and menopause status, more so than OMAT.

Keyphrases

insulin resistance
adipose tissue
metabolic syndrome
weight loss
type diabetes
oxidative stress
high fat diet induced
poor prognosis
weight gain
bariatric surgery
postmenopausal women
nitric oxide
fatty acid
small molecule
physical activity
nitric oxide synthase
long non coding rna
obese patients
protein protein