Development of a robust induced pluripotent stem cell atrial cardiomyocyte differentiation protocol to model atrial arrhythmia.
Jordan ThorpeMatthew D PerryOsvaldo ContrerasEmily HurleyGeorge ParkerRichard P HarveyAdam P HillJamie I VandenbergPublished in: Stem cell research & therapy (2023)
This method combines an enhanced atrial-like phenotype with robustness of differentiation, which will facilitate further research in human atrial arrhythmia and myopathies, while being economically viable for larger anti-arrhythmic drug screens.