Primary Antiphospholipid Syndrome Associated with Autoantibodies Against Golgi Bodies: A Case Report of a 32-Year-Old Female.
Neha Rani VermaSuprava PatelRachita NandaEli MohapatraPublished in: Indian journal of clinical biochemistry : IJCB (2018)
Antiphospholipid syndrome is an autoantibody mediated disorder characterised by thrombotic manifestations and/or obstetric morbidity. The autoantibodies are directed against phospholipid binding plasma proteins. Amongst the clinical features abdominal presentation is an unusual feature in this syndrome. We present the case report of a 32-year female whose complaints was abdominal pain for one week and no history of previous foetal loss, who responded well to warfarin and has not developed systemic lupus erythematous even after follow up. Characteristic of this patient is the appearance of auto antibodies against Golgi bodies. Although antinuclear antibodies are seen in patients of rheumatic disease like systemic lupus erythematous, its presence in individuals with unusual presentation of antiphospholipid syndrome may facilitate in diagnosis.
Keyphrases
- case report
- systemic lupus erythematosus
- abdominal pain
- end stage renal disease
- disease activity
- ejection fraction
- chronic kidney disease
- rheumatoid arthritis
- newly diagnosed
- venous thromboembolism
- atrial fibrillation
- endoplasmic reticulum
- prognostic factors
- randomized controlled trial
- deep learning
- fatty acid
- patient reported outcomes
- transcription factor
- drug induced