The food and biomedical applications of curcumin-loaded electrospun nanofibers: A comprehensive review.
Mohammadreza RostamiHanieh Kolahi AzarMojdeh SalehiShabnam Abedin DargoushHosein RostamaniGholamreza Jahed-KhanikiMahsa AlikordReza AghabeigiAzam AhmadiNima BeheshtizadehThomas J WebsterNima RezaeiPublished in: Critical reviews in food science and nutrition (2023)
Encapsulating curcumin (CUR) in nanocarriers such as liposomes, polymeric micelles, silica nanoparticles, protein-based nanocarriers, solid lipid nanoparticles, and nanocrystals could be efficient for a variety of industrial and biomedical applications. Nanofibers containing CUR represent a stable polymer-drug carrier with excellent surface-to-volume ratios for loading and cell interactions, tailored porosity for controlled CUR release, and diverse properties that fit the requirements for numerous applications. Despite the mentioned benefits, electrospinning is not capable of producing fibers from multiple polymers and biopolymers, and the product's effectiveness might be affected by various machine- and material-dependent parameters like the voltage and the flow rate of the electrospinning process. This review delves into the current and innovative recent research on nanofibers containing CUR and their various applications.
Keyphrases
- drug delivery
- drug release
- cancer therapy
- tissue engineering
- randomized controlled trial
- single cell
- systematic review
- wastewater treatment
- deep learning
- smoking cessation
- room temperature
- stem cells
- protein protein
- binding protein
- mesenchymal stem cells
- amino acid
- emergency department
- quantum dots
- small molecule
- climate change
- lactic acid