Altered plasma levels and tissue expression of fibroblast activation protein alpha in giant cell arteritis.

Shuang Xu William F JiemyAnnemieke M H BootsSuzanne ArendsYannick van SleenPieter H NienhuisKornelis S M van der Geest Peter HeeringaElisabeth BrouwerElisabeth Brouwer

Published in: Arthritis care & research (2024)

FAP expression in GCA is clearly modulated both in plasma and in vessels. FAP may be involved in the inflammatory and remodeling processes in GCA and have utility as target for imaging and therapeutic intervention.

Keyphrases

poor prognosis
giant cell
binding protein
randomized controlled trial
high resolution
protein protein
mass spectrometry
amino acid
photodynamic therapy
fluorescence imaging