The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C.
John V PluvinageJerry SunChristel ClaesRyan A FlynnMichael S HaneyTal IramXiangling MengRachel LindemannNicholas M RileyEmma DanhashJean Paul ChadarevianEmma TappDavid GateSravani KondapavulurInma CobosSundari ChettyAnca M PașcaSergiu P PașcaElizabeth M Berry-KravisCarolyn R BertozziMathew Blurton JonesTony Wyss-CorayPublished in: Science translational medicine (2021)
[Figure: see text].