Upregulation of cytidine deaminase in NAT1 knockout breast cancer cells.
Kyung U HongAfi H TagnedjiMark A DollKennedy M WallsDavid W HeinPublished in: Journal of cancer research and clinical oncology (2022)
The present findings suggest a novel therapeutic strategy to treat breast cancer with elevated NAT1 expression. For instance, NAT1 inhibition may be combined with cytotoxic nucleosides (e.g., 5fdC) for breast cancer treatment.