David W Hein

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 42

Top Venues

Archives of toxicology

PloS one

Cardiovascular toxicology

Genes

University of Louisville

University of Michigan (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Louisville

United States

Professor and Endowed Chair :: Pharmacology & Toxicology

University of North Dakota

United States

Professor and Chair :: Pharmacology & Toxicology

Morehouse School of Medicine

United States

Assistant, Associate, Full Professor and Chair :: Pharmacology

Education History

University of Michigan

United States

PHD :: Pharmacology

University of Wisconsin Eau Claire

United States

BSC :: Chemistry

Publications

Kennedy M Walls, Jonathan Y Joh, Kyung U Hong, David W Hein
Heterocyclic Amines Disrupt Lipid Homeostasis in Cryopreserved Human Hepatocytes. Cardiovascular toxicology (2024)
Kennedy M Walls, Jonathan Y Joh, Kyung U Hong, David W Hein
Heterocyclic Amines Disrupt Lipid Homeostasis in Cryopreserved Human Hepatocytes. Cardiovascular toxicology 24 (8) (2024)
Kennedy M Walls, Jonathan Y Joh, Kyung U Hong, David W Hein
Heterocyclic Amines Disrupt Lipid Homeostasis in Cryopreserved Human Hepatocytes. Cardiovascular toxicology (2024)
Kennedy M Walls, Jonathan Y Joh, Kyung U Hong, David W Hein
Heterocyclic Amines Disrupt Lipid Homeostasis in Cryopreserved Human Hepatocytes. Cardiovascular toxicology 24 (8) (2024)
David W Hein, Raúl A Salazar-González, Mark A Doll, Yu Zang
The effect of the rs1799931 G857A (G286E) polymorphism on N-acetyltransferase 2-mediated carcinogen metabolism and genotoxicity differs with heterocyclic amine exposure. Archives of toxicology (2023)
Mariam R Habil, David W Hein
Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity. Archives of toxicology 97 (6) (2023)
Mariam R Habil, David W Hein
Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity. Archives of toxicology 97 (6) (2023)
James T F Wise, Xinmin Yin, Xipeng Ma, Xiang Zhang, David W Hein
Stable Isotope Tracing Reveals an Altered Fate of Glucose in N -Acetyltransferase 1 Knockout Breast Cancer Cells. Genes 14 (4) (2023)
Mariam R Habil, David W Hein
Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity. Archives of toxicology (2023)
Mariam R Habil, Raúl A Salazar-González, Mark A Doll, David W Hein
Effect of N-acetyltransferase 2 genetic polymorphism on 4,4'-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress. Archives of toxicology 97 (6) (2023)
James T F Wise, Xinmin Yin, Xipeng Ma, Xiang Zhang, David W Hein
Stable Isotope Tracing Reveals an Altered Fate of Glucose in N -Acetyltransferase 1 Knockout Breast Cancer Cells. Genes 14 (4) (2023)
Mariam R Habil, David W Hein
Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity. Archives of toxicology 97 (6) (2023)
Mariam R Habil, Raúl A Salazar-González, Mark A Doll, David W Hein
Effect of N-acetyltransferase 2 genetic polymorphism on 4,4'-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress. Archives of toxicology 97 (6) (2023)
James T F Wise, Xinmin Yin, Xipeng Ma, Xiang Zhang, David W Hein
Stable Isotope Tracing Reveals an Altered Fate of Glucose in N -Acetyltransferase 1 Knockout Breast Cancer Cells. Genes 14 (4) (2023)
Mariam R Habil, Raúl A Salazar-González, Mark A Doll, David W Hein
Effect of N-acetyltransferase 2 genetic polymorphism on 4,4'-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress. Archives of toxicology 97 (6) (2023)
Mariam R Habil, David W Hein
Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity. Archives of toxicology 97 (6) (2023)
Mariam R Habil, Raúl A Salazar-González, Mark A Doll, David W Hein
Effect of N-acetyltransferase 2 genetic polymorphism on 4,4'-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress. Archives of toxicology (2023)
Kennedy M Walls, Kyung U Hong, David W Hein
Correction: Heterocyclic amines reduce insulin-induced AKT phosphorylation and induce gluconeogenic gene expression in human hepatocytes. Archives of toxicology (2023)
Kennedy M Walls, Kyung U Hong, David W Hein
Heterocyclic amines reduce insulin-induced AKT phosphorylation and induce gluconeogenic gene expression in human hepatocytes. Archives of toxicology (2023)
James T F Wise, Xinmin Yin, Xipeng Ma, Xiang Zhang, David W Hein
Stable Isotope Tracing Reveals an Altered Fate of Glucose in N -Acetyltransferase 1 Knockout Breast Cancer Cells. Genes 14 (4) (2023)
Mariam R Habil, Raúl A Salazar-González, Mark A Doll, David W Hein
N-acetyltransferase 2 acetylator genotype-dependent N-acetylation and toxicity of the arylamine carcinogen β-naphthylamine in cryopreserved human hepatocytes. Archives of toxicology 96 (12) (2022)
Islamiat Oladipupo, T'shura Ali, David W Hein, Kelly Pagidas, Henry Bohler, Mark A Doll, Merry Lynn Mann, Adrienne Gentry, Jasmine L Chiang, Rebecca C Pierson, Sashia Torres, Emily Reece, Kira C Taylor
Association between cigarette smoking and ovarian reserve among women seeking fertility care. PloS one 17 (12) (2022)
Mark A Doll, Andrew R Ray, Raúl A Salazar-González, Parag P Shah, Alexis A Vega, Sophia M Sears, Austin M Krueger, Kyung U Hong, Levi J Beverly, David W Hein
Deletion of arylamine N-acetyltransferase 1 in MDA-MB-231 human breast cancer cells reduces primary and secondary tumor growth in vivo with no significant effects on metastasis. Molecular carcinogenesis 61 (5) (2022)
Raúl A Salazar-González, Mark A Doll, David W Hein
N-acetyltransferase 2 genetic polymorphism modifies genotoxic and oxidative damage from new psychoactive substances. Archives of toxicology (2022)
Islamiat Oladipupo, T'shura Ali, David W Hein, Kelly Pagidas, Henry Bohler, Mark A Doll, Merry Lynn Mann, Adrienne Gentry, Jasmine L Chiang, Rebecca C Pierson, Sashia Torres, Emily Reece, Kira C Taylor
Association between cigarette smoking and ovarian reserve among women seeking fertility care. PloS one 17 (12) (2022)
Islamiat Oladipupo, T'shura Ali, David W Hein, Kelly Pagidas, Henry Bohler, Mark A Doll, Merry Lynn Mann, Adrienne Gentry, Jasmine L Chiang, Rebecca C Pierson, Sashia Torres, Emily Reece, Kira C Taylor
Association between cigarette smoking and ovarian reserve among women seeking fertility care. PloS one 17 (12) (2022)
Mariam R Habil, Raúl A Salazar-González, Mark A Doll, David W Hein
Differences in β-naphthylamine metabolism and toxicity in Chinese hamster ovary cell lines transfected with human CYP1A2 and NAT2*4, NAT2*5B or NAT2*7B N-acetyltransferase 2 haplotypes. Archives of toxicology 96 (11) (2022)
Islamiat Oladipupo, T'shura Ali, David W Hein, Kelly Pagidas, Henry Bohler, Mark A Doll, Merry Lynn Mann, Adrienne Gentry, Jasmine L Chiang, Rebecca C Pierson, Sashia Torres, Emily Reece, Kira C Taylor
Association between cigarette smoking and ovarian reserve among women seeking fertility care. PloS one 17 (12) (2022)
Islamiat Oladipupo, T'shura Ali, David W Hein, Kelly Pagidas, Henry Bohler, Mark A Doll, Merry Lynn Mann, Adrienne Gentry, Jasmine L Chiang, Rebecca C Pierson, Sashia Torres, Emily Reece, Kira C Taylor
Association between cigarette smoking and ovarian reserve among women seeking fertility care. PloS one 17 (12) (2022)
Kyung U Hong, Afi H Tagnedji, Mark A Doll, Kennedy M Walls, David W Hein
Upregulation of cytidine deaminase in NAT1 knockout breast cancer cells. Journal of cancer research and clinical oncology (2022)
Kyung U Hong, Raúl A Salazar-González, Kennedy M Walls, David W Hein
Transcriptional Regulation of Human Arylamine N-Acetyltransferase 2 Gene by Glucose and Insulin in Liver Cancer Cell Lines. Toxicological sciences : an official journal of the Society of Toxicology 190 (2) (2022)
Carmine S Leggett, Mark A Doll, Raúl A Salazar-González, Mariam R Habil, John O Trent, David W Hein
Identification and characterization of potent, selective, and efficacious inhibitors of human arylamine N-acetyltransferase 1. Archives of toxicology (2021)
Carmine S Leggett, Mark A Doll, J Christopher States, David W Hein
Acetylation of putative arylamine and alkylaniline carcinogens in immortalized human fibroblasts transfected with rapid and slow acetylator N-acetyltransferase 2 haplotypes. Archives of toxicology 95 (1) (2020)
Marcus W Stepp, Raúl A Salazar-González, Kyung U Hong, Mark A Doll, David W Hein
N-Acetyltransferase 1 Knockout Elevates Acetyl Coenzyme A Levels and Reduces Anchorage-Independent Growth in Human Breast Cancer Cell Lines. Journal of oncology 2019 (2019)
Raúl A Salazar-González, Xiaoyan Zhang, Mark A Doll, Angeliki Lykoudi, David W Hein
Role of the human N-acetyltransferase 2 genetic polymorphism in metabolism and genotoxicity of 4, 4'-methylenedianiline. Archives of toxicology 93 (8) (2019)
Kristin J Baldauf, Raúl A Salazar-González, Mark A Doll, William M Pierce, J Christopher States, David W Hein
Role of Human N-Acetyltransferase 2 Genetic Polymorphism on Aromatic Amine Carcinogen-Induced DNA Damage and Mutagenicity in a Chinese Hamster Ovary Cell Mutation Assay. Environmental and molecular mutagenesis 61 (2) (2019)
Marcus W Stepp, Mark A Doll, Samantha M Carlisle, J Christopher States, David W Hein
Genetic and small molecule inhibition of arylamine N-acetyltransferase 1 reduces anchorage-independent growth in human breast cancer cell line MDA-MB-231. Molecular carcinogenesis 57 (4) (2018)
Samantha M Carlisle, Patrick J Trainor, Mark A Doll, Marcus W Stepp, Carolyn M Klinge, David W Hein
Knockout of human arylamine N-acetyltransferase 1 (NAT1) in MDA-MB-231 breast cancer cells leads to increased reserve capacity, maximum mitochondrial capacity, and glycolytic reserve capacity. Molecular carcinogenesis 57 (11) (2018)
Cecily E Allen, Mark A Doll, David W Hein
N-Acetyltransferase 2 Genotype-Dependent N-Acetylation of Hydralazine in Human Hepatocytes. Drug metabolism and disposition: the biological fate of chemicals 45 (12) (2017)
Mark A Doll, David W Hein
Genetic heterogeneity among slow acetylator N-acetyltransferase 2 phenotypes in cryopreserved human hepatocytes. Archives of toxicology 91 (7) (2017)
David W Hein, Mark A Doll
Rabbit N-acetyltransferase 2 genotyping method to investigate role of acetylation polymorphism on N- and O-acetylation of aromatic and heterocyclic amine carcinogens. Archives of toxicology 91 (9) (2017)
David W Hein, Mark A Doll
Catalytic properties and heat stabilities of novel recombinant human N-acetyltransferase 2 allozymes support existence of genetic heterogeneity within the slow acetylator phenotype. Archives of toxicology 91 (8) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

David W Hein