Using meta-analysis and machine learning to investigate the transcriptional response of immune cells to Leishmania infection.

Zahra RezaeiAhmad TahmasebiBahman Pourabbas

Published in: PLoS neglected tropical diseases (2024)

These findings provide valuable insights into the molecular mechanisms underlying the response of immune system cells to Leishmania infection and offer novel potential targets for the therapeutic goals.

Keyphrases

machine learning
systematic review
induced apoptosis
gene expression
transcription factor
meta analyses
randomized controlled trial
signaling pathway
oxidative stress
endoplasmic reticulum stress
big data
deep learning
public health
human health
case control
cell death
global health
trypanosoma cruzi