Multicentre feasibility of multiple-breath washout in preschool children with cystic fibrosis and other lung diseases.

This study demonstrates that multicentre MBW in awake preschool children is feasible, even in centres previously naïve, with central coordination to assure standardised training, quality control and supervision. Our results support the use of LCI as multicentre end-point in clinical trials in awake preschoolers with CF.