Coronary Artery Disease Risk Variant Dampens the Expression of CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer in Endothelial Cells In Vitro.
Ilakya SelvarajanMinna U KaikkonenRu-Ting HuangJin LiJiayu ZhuPetri PölönenTiit ÖrdKadri ÕunapMehvash GodiwalaAnna Kathryn GolebiewskiAarthi RavindranKiira MäklinAnu ToropainenLindsey K StolzeMaximiliano ArcePeetra Ulrica MagnussonStephen J WhiteCasey E RomanoskiMerja HeinäniemiJohanna P LaakkonenYun FangMinna Kaikkonen-MäättäPublished in: Arteriosclerosis, thrombosis, and vascular biology (2024)
expression could provide important steps toward understanding the genetic regulation of shear stress signaling responses.
Keyphrases
- poor prognosis
- coronary artery disease
- endothelial cells
- binding protein
- long non coding rna
- percutaneous coronary intervention
- gene expression
- type diabetes
- cardiovascular disease
- genome wide
- cancer therapy
- cardiovascular events
- coronary artery bypass grafting
- oxidative stress
- drug delivery
- left ventricular
- dna methylation
- atrial fibrillation
- ejection fraction