Merja Heinäniemi

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 22

Top Venues

Blood advances

Arteriosclerosis, thrombosis, and vascular biology

Genome biology

Blood

University of Eastern Finland

University of Kuopio (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Eastern Finland Jan 01 2017

Finland

Associate Professor (Tenure track) :: Medicine

Education History

University of Kuopio - Mar 31 2007

Finland

PHD :: Biochemistry

University of Kuopio

Finland

MSC :: Biochemistry

Publications

Gaia Gentile, Teresa Poggio, Antonella Catalano, Minna Voutilainen, Mari Lahnalampi, Marta Andrade-Martinez, Tobias Ma, Roman Sankowski, Lina Goncharenko, Stefan Tholen, Kyuho Han, David W Morgens, Marco Prinz, Michael Lübbert, Sophia Engel, Tanja Nicole Hartmann, Gunnar Cario, Martin Schrappe, Lennart Lenk, Martin Stanulla, Justus Duyster, Peter Bronsert, Michael Bassik, Michael L Cleary, Oliver Schilling, Merja Heinäniemi, Jesus Duque-Afonso
Development of combination therapies with BTK inhibitors and dasatinib to treat CNS-infiltrating E2A-PBX1+/preBCR+ ALL. Blood advances (2024)
Gaia Gentile, Teresa Poggio, Antonella Catalano, Minna Voutilainen, Mari Lahnalampi, Marta Andrade-Martinez, Tobias Ma, Roman Sankowski, Lina Goncharenko, Stefan Tholen, Kyuho Han, David W Morgens, Marco Prinz, Michael Lübbert, Sophia Engel, Tanja Nicole Hartmann, Gunnar Cario, Martin Schrappe, Lennart Lenk, Martin Stanulla, Justus Duyster, Peter Bronsert, Michael C Bassik, Michael L Cleary, Oliver Schilling, Merja Heinäniemi, Jesus Duque-Afonso
Development of combination therapies with BTK inhibitors and dasatinib to treat CNS-infiltrating E2A-PBX1+/preBCR+ ALL. Blood advances 8 (11) (2024)
Ilakya Selvarajan, Minna U Kaikkonen, Ru-Ting Huang, Jin Li, Jiayu Zhu, Petri Pölönen, Tiit Örd, Kadri Õunap, Mehvash Godiwala, Anna Kathryn Golebiewski, Aarthi Ravindran, Kiira Mäklin, Anu Toropainen, Lindsey K Stolze, Maximiliano Arce, Peetra Ulrica Magnusson, Stephen J White, Casey E Romanoski, Merja Heinäniemi, Johanna P Laakkonen, Yun Fang
Coronary Artery Disease Risk Variant Dampens the Expression of CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer in Endothelial Cells In Vitro. Arteriosclerosis, thrombosis, and vascular biology 44 (6) (2024)
Gaia Gentile, Teresa Poggio, Antonella Catalano, Minna Voutilainen, Mari Lahnalampi, Marta Andrade-Martinez, Tobias Ma, Roman Sankowski, Lina Goncharenko, Stefan Tholen, Kyuho Han, David W Morgens, Marco Prinz, Michael Lübbert, Sophia Engel, Tanja Nicole Hartmann, Gunnar Cario, Martin Schrappe, Lennart Lenk, Martin Stanulla, Justus Duyster, Peter Bronsert, Michael C Bassik, Michael L Cleary, Oliver Schilling, Merja Heinäniemi, Jesus Duque-Afonso
Development of combination therapies with BTK inhibitors and dasatinib to treat CNS-infiltrating E2A-PBX1+/preBCR+ ALL. Blood advances 8 (11) (2024)
Alena Malyukova, Mari Lahnalampi, Ton Falqués-Costa, Petri Pölönen, Mikko Sipola, Juha Mehtonen, Susanna Teppo, Karen Akopyan, Johanna Viiliainen, Olli Lohi, Anna K Hagström-Andersson, Merja Heinäniemi, Olle Sangfelt
Sequential drug treatment targeting cell cycle and cell fate regulatory programs blocks non-genetic cancer evolution in acute lymphoblastic leukemia. Genome biology 25 (1) (2024)
Ilakya Selvarajan, Minna U Kaikkonen, Ru-Ting Huang, Jin Li, Jiayu Zhu, Petri Pölönen, Tiit Örd, Kadri Õunap, Mehvash Godiwala, Anna Kathryn Golebiewski, Aarthi Ravindran, Kiira Mäklin, Anu Toropainen, Lindsey K Stolze, Maximiliano Arce, Peetra Ulrica Magnusson, Stephen J White, Casey E Romanoski, Merja Heinäniemi, Johanna P Laakkonen, Yun Fang
Coronary Artery Disease Risk Variant Dampens the Expression of CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer in Endothelial Cells In Vitro. Arteriosclerosis, thrombosis, and vascular biology 44 (6) (2024)
Gaia Gentile, Teresa Poggio, Antonella Catalano, Minna Voutilainen, Mari Lahnalampi, Marta Andrade-Martinez, Tobias Ma, Roman Sankowski, Lina Goncharenko, Stefan Tholen, Kyuho Han, David W Morgens, Marco Prinz, Michael Lübbert, Sophia Engel, Tanja Nicole Hartmann, Gunnar Cario, Martin Schrappe, Lennart Lenk, Martin Stanulla, Justus Duyster, Peter Bronsert, Michael C Bassik, Michael L Cleary, Oliver Schilling, Merja Heinäniemi, Jesus Duque-Afonso
Development of combination therapies with BTK inhibitors and dasatinib to treat CNS-infiltrating E2A-PBX1+/preBCR+ ALL. Blood advances 8 (11) (2024)
Gaia Gentile, Teresa Poggio, Antonella Catalano, Minna Voutilainen, Mari Lahnalampi, Marta Andrade-Martinez, Tobias Ma, Roman Sankowski, Lina Goncharenko, Stefan Tholen, Kyuho Han, David W Morgens, Marco Prinz, Michael Lübbert, Sophia Engel, Tanja Nicole Hartmann, Gunnar Cario, Martin Schrappe, Lennart Lenk, Martin Stanulla, Justus Duyster, Peter Bronsert, Michael C Bassik, Michael L Cleary, Oliver Schilling, Merja Heinäniemi, Jesus Duque-Afonso
Development of combination therapies with BTK inhibitors and dasatinib to treat CNS-infiltrating E2A-PBX1+/preBCR+ ALL. Blood advances 8 (11) (2024)
Alena Malyukova, Mari Lahnalampi, Ton Falqués-Costa, Petri Pölönen, Mikko Sipola, Juha Mehtonen, Susanna Teppo, Karen Akopyan, Johanna Viiliainen, Olli Lohi, Anna K Hagström-Andersson, Merja Heinäniemi, Olle Sangfelt
Sequential drug treatment targeting cell cycle and cell fate regulatory programs blocks non-genetic cancer evolution in acute lymphoblastic leukemia. Genome biology 25 (1) (2024)
Ilakya Selvarajan, Minna U Kaikkonen, Ru-Ting Huang, Jin Li, Jiayu Zhu, Petri Pölönen, Tiit Örd, Kadri Õunap, Mehvash Godiwala, Anna Kathryn Golebiewski, Aarthi Ravindran, Kiira Mäklin, Anu Toropainen, Lindsey K Stolze, Maximiliano Arce, Peetra Ulrica Magnusson, Stephen J White, Casey E Romanoski, Merja Heinäniemi, Johanna P Laakkonen, Yun Fang
Coronary Artery Disease Risk Variant Dampens the Expression of CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer in Endothelial Cells In Vitro. Arteriosclerosis, thrombosis, and vascular biology 44 (6) (2024)
Ilakya Selvarajan, Minna U Kaikkonen, Ru-Ting Huang, Jin Li, Jiayu Zhu, Petri Pölönen, Tiit Örd, Kadri Õunap, Mehvash Godiwala, Anna Kathryn Golebiewski, Aarthi Ravindran, Kiira Mäklin, Anu Toropainen, Lindsey K Stolze, Maximiliano Arce, Peetra Ulrica Magnusson, Stephen J White, Casey E Romanoski, Merja Heinäniemi, Johanna P Laakkonen, Yun Fang, Minna Kaikkonen-Määttä
Coronary Artery Disease Risk Variant Dampens the Expression of CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer in Endothelial Cells In Vitro. Arteriosclerosis, thrombosis, and vascular biology (2024)
Alena Malyukova, Mari Lahnalampi, Ton Falqués-Costa, Petri Pölönen, Mikko Sipola, Juha Mehtonen, Susanna Teppo, Karen Akopyan, Johanna Viiliainen, Olli Lohi, Anna K Hagström-Andersson, Merja Heinäniemi, Olle Sangfelt
Sequential drug treatment targeting cell cycle and cell fate regulatory programs blocks non-genetic cancer evolution in acute lymphoblastic leukemia. Genome biology 25 (1) (2024)
Heikki Kuusanmäki, Olli Dufva, Markus Vähä-Koskela, Aino-Maija Leppä, Jani Huuhtanen, Ida Maria Vänttinen, Petra Johanna Nygren, Jay Klievink, Jonas Otto Vilhelm Bouhlal, Petri Pölönen, Qi Zhang, Shady Adnan-Awad, Cristina Mancebo-Pérez, Joseph Saad, Juho J Miettinen, Komal Kumar Javarappa, Sofia Aakko, Tanja Ruokoranta, Samuli Eldfors, Merja Heinäniemi, Kim Theilgaard-Mönch, Ulla Wartiovaara-Kautto, Mikko A I Keränen, Kimmo Porkka, Marina Konopleva, Krister Wennerberg, Mika Kontro, Caroline A Heckman, Mohamed El Missiry
Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia. Blood (2022)
Heikki Kuusanmäki, Olli Dufva, Markus Vähä-Koskela, Aino-Maija Leppä, Jani Huuhtanen, Ida Maria Vänttinen, Petra Johanna Nygren, Jay Klievink, Jonas Otto Vilhelm Bouhlal, Petri Pölönen, Qi Zhang, Shady Adnan-Awad, Cristina Mancebo-Pérez, Joseph Saad, Juho J Miettinen, Komal Kumar Javarappa, Sofia Aakko, Tanja Ruokoranta, Samuli Eldfors, Merja Heinäniemi, Kim Theilgaard-Mönch, Ulla Wartiovaara-Kautto, Mikko A I Keränen, Kimmo Porkka, Marina Konopleva, Krister Wennerberg, Mika Kontro, Caroline A Heckman, Mohamed El Missiry
Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia. Blood (2022)
Saara Laukkanen, Alexandra Veloso, Chuan Yan, Laura Oksa, Eric J Alpert, Daniel Do, Noora Hyvärinen, Karin McCarthy, Abhinav Adhikari, Qiqi Yang, Sowmya Iyer, Sara P Garcia, Annukka Pello, Tanja Ruokoranta, Sanni Moisio, Sadiksha Adhikari, Jeffrey A Yoder, Kayleigh Gallagher, Lauren Whelton, James R Allen, Alexander H Jin, Siebe Loontiens, Merja Heinäniemi, Michelle Kelliher, Caroline A Heckman, Olli Lohi, David M Langenau
Therapeutic targeting of LCK tyrosine kinase and mTOR signaling in T-cell acute lymphoblastic leukemia. Blood 140 (17) (2022)
Saara Laukkanen, Laura Oksa, Atte Nikkilä, Mari Lahnalampi, Mataleena Parikka, Masafumi Seki, Junko Takita, Sofie Degerman, Charles E de Bock, Merja Heinäniemi, Olli Lohi
SIX6 is a TAL1-regulated transcription factor in T-ALL and associated with inferior outcome. Leukemia & lymphoma 61 (13) (2020)
Lai N Chan, Mark A Murakami, Mark E Robinson, Rebecca Caeser, Teresa Sadras, Jaewoong Lee, Kadriye Nehir Cosgun, Kohei Kume, Vishal Khairnar, Gang Xiao, Mohamed A Ahmed, Eamon Aghania, Gauri Deb, Christian Hurtz, Seyedmehdi Shojaee, Chao Hong, Petri Pölönen, Matthew A Nix, Zhengshan Chen, Chun Wei Chen, Jianjun Chen, Andreas Vogt, Merja Heinäniemi, Olli Lohi, Arun P Wiita, Shai Izraeli, Huimin Geng, David M Weinstock, Markus Müschen
Signalling input from divergent pathways subverts B cell transformation. Nature 583 (7818) (2020)
Juha Mehtonen, Susanna Teppo, Mari Lahnalampi, Aleksi Kokko, Riina Kaukonen, Laura Oksa, Maria Bouvy-Liivrand, Alena Malyukova, Artturi Mäkinen, Saara Laukkanen, Petri I Mäkinen, Samuli Rounioja, Pekka Ruusuvuori, Olle Sangfelt, Riikka Lund, Tapio Lönnberg, Olli Lohi, Merja Heinäniemi
Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1-positive pediatric leukemia identifies drug-targetable transcription factor activities. Genome medicine 12 (1) (2020)
Petri Pölönen, Juha Mehtonen, Jake Lin, Thomas Liuksiala, Sergei Häyrynen, Susanna Teppo, Artturi Mäkinen, Ashwini Kumar, Disha Malani, Virva Pohjolainen, Kimmo Porkka, Caroline A Heckman, Patrick May, Ville Hautamäki, Kirsi J Granberg, Olli Lohi, Matti Nykter, Merja Heinäniemi
Hemap: An Interactive Online Resource for Characterizing Molecular Phenotypes across Hematologic Malignancies. Cancer research 79 (10) (2019)
Susanna Teppo, Merja Heinäniemi, Olli Lohi
Deregulation of the non-coding genome in leukemia. RNA biology 14 (7) (2017)
Merja Heinäniemi, Tapio Vuorenmaa, Susanna Teppo, Minna U Kaikkonen, Maria Bouvy-Liivrand, Juha Mehtonen, Henri Niskanen, Vasilios Zachariadis, Saara Laukkanen, Thomas Liuksiala, Kaisa Teittinen, Olli Lohi
Transcription-coupled genetic instability marks acute lymphoblastic leukemia structural variation hotspots. eLife 5 (2016)
Susanna Teppo, Saara Laukkanen, Thomas Liuksiala, Jessica Nordlund, Mikko Oittinen, Kaisa Teittinen, Toni Grönroos, Pascal St-Onge, Daniel Sinnett, Ann-Christine Syvänen, Matti Nykter, Keijo Viiri, Merja Heinäniemi, Olli Lohi
Genome-wide repression of eRNA and target gene loci by the ETV6-RUNX1 fusion in acute leukemia. Genome research 26 (11) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Merja Heinäniemi