Recent Trends in Exhaled Breath Diagnosis Using an Artificial Olfactory System.
Chuntae KimIruthayapandi Selestin RajaJong-Min LeeJong Ho LeeMoon Sung KangSeok Hyun LeeJin-Woo OhDong Wook HanPublished in: Biosensors (2021)
Artificial olfactory systems are needed in various fields that require real-time monitoring, such as healthcare. This review introduces cases of detection of specific volatile organic compounds (VOCs) in a patient's exhaled breath and discusses trends in disease diagnosis technology development using artificial olfactory technology that analyzes exhaled human breath. We briefly introduce algorithms that classify patterns of odors (VOC profiles) and describe artificial olfactory systems based on nanosensors. On the basis of recently published research results, we describe the development trend of artificial olfactory systems based on the pattern-recognition gas sensor array technology and the prospects of application of this technology to disease diagnostic devices. Medical technologies that enable early monitoring of health conditions and early diagnosis of diseases are crucial in modern healthcare. By regularly monitoring health status, diseases can be prevented or treated at an early stage, thus increasing the human survival rate and reducing the overall treatment costs. This review introduces several promising technical fields with the aim of developing technologies that can monitor health conditions and diagnose diseases early by analyzing exhaled human breath in real time.
Keyphrases
- healthcare
- endothelial cells
- early stage
- induced pluripotent stem cells
- public health
- pluripotent stem cells
- randomized controlled trial
- health information
- deep learning
- squamous cell carcinoma
- systematic review
- mass spectrometry
- high throughput
- health insurance
- human health
- loop mediated isothermal amplification
- carbon dioxide
- sensitive detection