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High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer.

Chelsea MayohJie MaoJinhan XieGabor TaxShu-Oi ChowRoxanne CadizKarina PazakyPaulette BarahonaPamela AjuyahPeter TrebilcockAngela MalquoriKate GuntherAnica AvilaDoo Young YunStephanie AlfredAnjana GopalakrishnanAlvin KamiliMarie WongMark J CowleySophie JessopLoretta M S LauToby N TrahairDavid S ZieglerJamie I FletcherAndrew J GiffordMaria TsoliGlenn M MarshallMichelle HaberVanessa TyrrellTimothy W FailesGreg M ArndtRichard B LockPaul G EkertM Emmy M Dolman
Published in: Cancer research (2023)
Integrating HTS with molecular profiling is a powerful tool for expanding precision medicine to support drug treatment recommendations and broaden the therapeutic options available to high-risk pediatric cancers.
Keyphrases
  • high throughput
  • single cell
  • papillary thyroid
  • young adults
  • childhood cancer
  • genome wide
  • adverse drug
  • single molecule
  • dna methylation
  • electronic health record
  • smoking cessation