David S Ziegler (David Ziegler)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 44

Top Topics

Childhood Cancer

Histone Deacetylase

Acute Lymphoblastic Leukemia

Top Venues

Nature medicine

Targeted oncology

This page only lists publications with an associated author ORCID identifier.

Publications

Loretta M S Lau, Dong Anh K Khoung-Quang, Chelsea Mayoh, Marie Wong, Paulette Barahona, Pamela Ajuyah, Akanksha Senapati, Sumanth Nagabushan, Alexandra Sherstyuk, Ann-Kristin Altekoester, Noemi A Fuentes-Bolanos, Veronica Yeung, Ashleigh Sullivan, Natacha Omer, Yonatan Diamond, Sophie Jessop, Lauren Battaglia, Nataliya Zhukova, Lujing Cui, Angela Lin, Andrew J Gifford, Emmy D G Fleuren, Luciano Dalla-Pozza, Andrew S Moore, Seong-Lin Khaw, David D Eisenstat, Nicholas G Gottardo, Paul J Wood, Heather Tapp, Frank Alvaro, Geoffrey McCowage, Wayne Nicholls, Jordan R Hansford, Neevika Manoharan, Rishi Sury Kotecha, Marion K Mateos, Richard B Lock, Vanessa Tyrrell, Michelle Haber, Toby N Trahair, Mark J Cowley, Paul G Ekert, Glenn M Marshall, David S Ziegler
Precision-guided treatment in high-risk pediatric cancers. Nature medicine (2024)
Kate Hetherington, Claire E Wakefield, Brittany C McGill, Katherine M Tucker, Mark W Donoghoe, Rebecca Daly, Jacqueline D Hunter, Mandy Ballinger, Noemi A Fuentes-Bolanos, David S Ziegler
When genetics and pediatric cancer collide: Understanding and optimizing families' experiences. Neuro-oncology advances 6 (1) (2024)
Louise Evans, Rick Walker, Jennifer MacDiarmid, Himanshu Brahmbhatt, Antoinette Anazodo, Geoffrey McCowage, Andrew J Gifford, Maria Kavallaris, Toby Trahair, David S Ziegler
A Phase 1 Study of Intravenous EGFR-ErbituxEDVsMIT in Children with Solid or CNS Tumours Expressing Epidermal Growth Factor Receptor. Targeted oncology (2024)
Loretta M S Lau, Dong Anh K Khoung-Quang, Chelsea Mayoh, Marie Wong, Paulette Barahona, Pamela Ajuyah, Akanksha Senapati, Sumanth Nagabushan, Alexandra Sherstyuk, Ann-Kristin Altekoester, Noemi A Fuentes-Bolanos, Veronica Yeung, Ashleigh Sullivan, Natacha Omer, Yonatan Diamond, Sophie Jessop, Lauren Battaglia, Nataliya Zhukova, Lujing Cui, Angela Lin, Andrew J Gifford, Emmy D G Fleuren, Luciano Dalla-Pozza, Andrew S Moore, Seong-Lin Khaw, David D Eisenstat, Nicholas G Gottardo, Paul J Wood, Heather Tapp, Frank Alvaro, Geoffrey McCowage, Wayne Nicholls, Jordan R Hansford, Neevika Manoharan, Rishi Sury Kotecha, Marion K Mateos, Richard B Lock, Vanessa Tyrrell, Michelle Haber, Toby N Trahair, Mark J Cowley, Paul G Ekert, Glenn M Marshall, David S Ziegler
Precision-guided treatment in high-risk pediatric cancers. Nature medicine 30 (7) (2024)
Louise Evans, Rick Walker, Jennifer MacDiarmid, Himanshu Brahmbhatt, Antoinette Anazodo, Geoffrey McCowage, Andrew J Gifford, Maria Kavallaris, Toby Trahair, David S Ziegler
A Phase 1 Study of Intravenous EGFR-ErbituxEDVsMIT in Children with Solid or CNS Tumours Expressing Epidermal Growth Factor Receptor. Targeted oncology 19 (3) (2024)
Kate Hetherington, Claire E Wakefield, Brittany C McGill, Katherine M Tucker, Mark W Donoghoe, Rebecca Daly, Jacqueline D Hunter, Mandy Ballinger, Noemi A Fuentes-Bolanos, David S Ziegler
When genetics and pediatric cancer collide: Understanding and optimizing families' experiences. Neuro-oncology advances 6 (1) (2024)
Louise Evans, Rick Walker, Jennifer MacDiarmid, Himanshu Brahmbhatt, Antoinette Anazodo, Geoffrey McCowage, Andrew J Gifford, Maria Kavallaris, Toby Trahair, David S Ziegler
A Phase 1 Study of Intravenous EGFR-ErbituxEDVsMIT in Children with Solid or CNS Tumours Expressing Epidermal Growth Factor Receptor. Targeted oncology 19 (3) (2024)
David S Ziegler, Rebecca Lehmann, David D Eisenstat
A paradigm shift in how we treat pediatric low-grade glioma-Targeting the molecular drivers. Neuro-oncology 26 (4) (2024)
Loretta M S Lau, Dong Anh K Khoung-Quang, Chelsea Mayoh, Marie Wong, Paulette Barahona, Pamela Ajuyah, Akanksha Senapati, Sumanth Nagabushan, Alexandra Sherstyuk, Ann-Kristin Altekoester, Noemi A Fuentes-Bolanos, Veronica Yeung, Ashleigh Sullivan, Natacha Omer, Yonatan Diamond, Sophie Jessop, Lauren Battaglia, Nataliya Zhukova, Lujing Cui, Angela Lin, Andrew J Gifford, Emmy D G Fleuren, Luciano Dalla-Pozza, Andrew S Moore, Seong-Lin Khaw, David D Eisenstat, Nicholas G Gottardo, Paul J Wood, Heather Tapp, Frank Alvaro, Geoffrey McCowage, Wayne Nicholls, Jordan R Hansford, Neevika Manoharan, Rishi Sury Kotecha, Marion K Mateos, Richard B Lock, Vanessa Tyrrell, Michelle Haber, Toby N Trahair, Mark J Cowley, Paul G Ekert, Glenn M Marshall, David S Ziegler
Precision-guided treatment in high-risk pediatric cancers. Nature medicine 30 (7) (2024)
Loretta M S Lau, Dong Anh K Khoung-Quang, Chelsea Mayoh, Marie Wong, Paulette Barahona, Pamela Ajuyah, Akanksha Senapati, Sumanth Nagabushan, Alexandra Sherstyuk, Ann-Kristin Altekoester, Noemi A Fuentes-Bolanos, Veronica Yeung, Ashleigh Sullivan, Natacha Omer, Yonatan Diamond, Sophie Jessop, Lauren Battaglia, Nataliya Zhukova, Lujing Cui, Angela Lin, Andrew J Gifford, Emmy D G Fleuren, Luciano Dalla-Pozza, Andrew S Moore, Seong-Lin Khaw, David D Eisenstat, Nicholas G Gottardo, Paul J Wood, Heather Tapp, Frank Alvaro, Geoffrey McCowage, Wayne Nicholls, Jordan R Hansford, Neevika Manoharan, Rishi Sury Kotecha, Marion K Mateos, Richard B Lock, Vanessa Tyrrell, Michelle Haber, Toby N Trahair, Mark J Cowley, Paul G Ekert, Glenn M Marshall, David S Ziegler
Precision-guided treatment in high-risk pediatric cancers. Nature medicine 30 (7) (2024)
Louise Evans, Rick Walker, Jennifer MacDiarmid, Himanshu Brahmbhatt, Antoinette Anazodo, Geoffrey McCowage, Andrew J Gifford, Maria Kavallaris, Toby Trahair, David S Ziegler
A Phase 1 Study of Intravenous EGFR-ErbituxEDVsMIT in Children with Solid or CNS Tumours Expressing Epidermal Growth Factor Receptor. Targeted oncology 19 (3) (2024)
Loretta M S Lau, Dong Anh K Khoung-Quang, Chelsea Mayoh, Marie Wong, Paulette Barahona, Pamela Ajuyah, Akanksha Senapati, Sumanth Nagabushan, Alexandra Sherstyuk, Ann-Kristin Altekoester, Noemi A Fuentes-Bolanos, Veronica Yeung, Ashleigh Sullivan, Natacha Omer, Yonatan Diamond, Sophie Jessop, Lauren Battaglia, Nataliya Zhukova, Lujing Cui, Angela Lin, Andrew J Gifford, Emmy D G Fleuren, Luciano Dalla-Pozza, Andrew S Moore, Seong-Lin Khaw, David D Eisenstat, Nicholas G Gottardo, Paul J Wood, Heather Tapp, Frank Alvaro, Geoffrey McCowage, Wayne Nicholls, Jordan R Hansford, Neevika Manoharan, Rishi Sury Kotecha, Marion K Mateos, Richard B Lock, Vanessa Tyrrell, Michelle Haber, Toby N Trahair, Mark J Cowley, Paul G Ekert, Glenn M Marshall, David S Ziegler
Precision-guided treatment in high-risk pediatric cancers. Nature medicine 30 (7) (2024)
Louise Evans, Rick Walker, Jennifer MacDiarmid, Himanshu Brahmbhatt, Antoinette Anazodo, Geoffrey McCowage, Andrew J Gifford, Maria Kavallaris, Toby Trahair, David S Ziegler
A Phase 1 Study of Intravenous EGFR-ErbituxEDVsMIT in Children with Solid or CNS Tumours Expressing Epidermal Growth Factor Receptor. Targeted oncology 19 (3) (2024)
Loretta M S Lau, Dong Anh K Khoung-Quang, Chelsea Mayoh, Marie Wong, Paulette Barahona, Pamela Ajuyah, Akanksha Senapati, Sumanth Nagabushan, Alexandra Sherstyuk, Ann-Kristin Altekoester, Noemi A Fuentes-Bolanos, Veronica Yeung, Ashleigh Sullivan, Natacha Omer, Yonatan Diamond, Sophie Jessop, Lauren Battaglia, Nataliya Zhukova, Lujing Cui, Angela Lin, Andrew J Gifford, Emmy D G Fleuren, Luciano Dalla-Pozza, Andrew S Moore, Seong-Lin Khaw, David D Eisenstat, Nicholas G Gottardo, Paul J Wood, Heather Tapp, Frank Alvaro, Geoffrey McCowage, Wayne Nicholls, Jordan R Hansford, Neevika Manoharan, Rishi Sury Kotecha, Marion K Mateos, Richard B Lock, Vanessa Tyrrell, Michelle Haber, Toby N Trahair, Mark J Cowley, Paul G Ekert, Glenn M Marshall, David S Ziegler
Precision-guided treatment in high-risk pediatric cancers. Nature medicine 30 (7) (2024)
David S Ziegler, Rebecca Lehmann, David D Eisenstat
A paradigm shift in how we treat pediatric low-grade glioma-Targeting the molecular drivers. Neuro-oncology 26 (4) (2024)
Lindsay B Kilburn, Dong Anh K Khoung-Quang, Jordan R Hansford, Daniel Landi, Jasper van der Lugt, Sarah E S Leary, Pablo Hernáiz Driever, Simon Bailey, Sébastien Perreault, Geoffrey McCowage, Angela J Waanders, David S Ziegler, Olaf Witt, Patricia A Baxter, Hyoung Jin Kang, Timothy E Hassall, Jung Woo Han, Darren R Hargrave, Andrea T Flynn, Michal Yalon Oren, Helen Toledano, Valérie Larouche, Cassie N Kline, Mohamed S Abdelbaki, Nada Jabado, Nicholas G Gottardo, Nicolas U Gerber, Nicholas S Whipple, Devorah Segal, Susan N Chi, Liat Oren, Enrica E K Tan, Sabine Mueller, Izzy Cornelio, Lisa McLeod, Xin Zhao, Ashley Walter, Daniel Da Costa, Peter Manley, Samuel C Blackman, Roger J Packer, Karsten Nysom
Author Correction: The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial. Nature medicine (2024)
Anahid Ehteda, Aaminah Khan, Gayathiri Rajakumar, Anne S Vanniasinghe, Anjana Gopalakrishnan, Jie Liu, Maria Tsoli, David S Ziegler
Microtubule-targeting combined with HDAC inhibition is a novel therapeutic strategy for Diffuse Intrinsic Pontine Gliomas. Molecular cancer therapeutics (2023)
Lindsay B Kilburn, Dong Anh K Khoung-Quang, Jordan R Hansford, Daniel Landi, Jasper van der Lugt, Sarah E S Leary, Pablo Hernáiz Driever, Simon Bailey, Sébastien Perreault, Geoffrey McCowage, Angela J Waanders, David S Ziegler, Olaf Witt, Patricia A Baxter, Hyoung Jin Kang, Timothy E Hassall, Jung Woo Han, Darren R Hargrave, Andrea T Flynn, Michal Yalon Oren, Helen Toledano, Valérie Larouche, Cassie N Kline, Mohamed S Abdelbaki, Nada Jabado, Nicholas G Gottardo, Nicolas U Gerber, Nicholas S Whipple, Devorah Segal, Susan N Chi, Liat Oren, Enrica E K Tan, Sabine Mueller, Izzy Cornelio, Lisa McLeod, Xin Zhao, Ashley Walter, Daniel Da Costa, Peter Manley, Samuel C Blackman, Roger J Packer, Karsten Nysom
The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial. Nature medicine (2023)
Rebecca Daly, Kate Hetherington, Emily Hazell, Bethany R Wadling, Vanessa Tyrrell, Katherine M Tucker, Glenn M Marshall, David S Ziegler, Loretta M S Lau, Toby N Trahair, Tracey A O'Brien, Kiri Collins, Andrew J Gifford, Michelle Haber, Mark Pinese, David Malkin, Mark J Cowley, Jonathan Karpelowsky, Donna Drew, Chris Jacobs, Claire E Wakefield
Precision Medicine Is Changing the Roles of Healthcare Professionals, Scientists, and Research Staff: Learnings from a Childhood Cancer Precision Medicine Trial. Journal of personalized medicine 13 (7) (2023)
Benedicte Grebstad Tune, Heena Sareen, Branka Powter, Smadar Kahana-Edwin, Adam Cooper, Eng-Siew Koh, Cheok S Lee, Joseph W Po, Geoff McCowage, Mark Dexter, Lucy E Cain, Geraldine O'Neill, Victoria Prior, Jonathan Karpelowsky, Maria Tsoli, Lars Oliver Baumbusch, David S Ziegler, Tara Laurine Roberts, Paul DeSouza, Therese Maria Becker, Yafeng Ma
From Pediatric to Adult Brain Cancer: Exploring Histone H3 Mutations in Australian Brain Cancer Patients. Biomedicines 11 (11) (2023)
Emily C Hardin, Simone Schmid, Alexander Sommerkamp, Carina Bodden, Anna-Elisa Heipertz, Philipp Sievers, Andrea Wittmann, Till Milde, Stefan M Pfister, Andreas von Deimling, Svea Horn, Nina A Herz, Michèle Simon, Ashwyn A Perera, Amedeo Azizi, Ofelia Cruz, Sarah Curry, An Van Damme, Miklos Garami, Darren Hargrave, Antonis Kattamis, Barbara Faganel Kotnik, Päivi Maria Lähteenmäki, Katrin Scheinemann, Antoinette Y N Schouten-van Meeteren, Astrid Sehested, Elisabetta Viscardi, Ole Mikal Wormdal, Michal Zapotocky, David S Ziegler, Arend Koch, Pablo Hernáiz Driever, Olaf Witt, David Capper, Felix Sahm, David T W Jones, Cornelis M van Tilburg
LOGGIC Core BioClinical Data Bank: Added clinical value of RNA-Seq in an international molecular diagnostic registry for pediatric low-grade glioma patients. Neuro-oncology (2023)
Anirban Das, Nicholas R Fernandez, Adrian B Levine, Vanessa Bianchi, Lucie K Stengs, Jiil Chung, Logine Negm, Jose Rafael Dimayacyac, Yuan Chang, Liana Nobre, Ayse Bahar Ercan, Santiago Sánchez-Ramírez, Sumedha Sudhaman, Melissa Edwards, Larouche Valérie, David Samuel, An Van Damme, David Gass, David S Ziegler, Stefan S Bielack, Carl J Koschmann, Shayna Zelcer, Michal Yalon-Oren, Gadi Abede Campino, Tomasz Sarosiek, Kim E Nichols, Rebecca Loret De Mola, Kevin Bielamowicz, Magnus Sabel, Charlotta A Frojd, Matthew D Wood, Jason M Glover, Yi-Yen Lee, Magimairajan Issai Vanan, Jenny K Adamski, Sébastien Perreault, Omar Chamdine, Magnus Aassved Hjort, Michal Zápotocký, Fernando Carceller, Erin Wright, Ivana Fedorakova, Alexander Lossos, Ryuma Tanaka, Michael Philip Osborn, Deborah T Blumenthal, Melyssa Aronson, Ute Bartels, Annie Huang, Vijay Ramsawami, David Malkin, Adam Shlien, Anita Villani, Peter B Dirks, Trevor J Pugh, Gad A Getz, Yosef E Maruvka, Derek S Tsang, Birgit Betina Ertl-Wagner, Cynthia Hawkins, Eric Bouffet, Daniel A Morgenstern, Uri Tabori
Combined immunotherapy improves outcome for replication repair deficient (RRD) high-grade glioma failing anti-PD1 monotherapy: A report from the International RRD Consortium. Cancer discovery (2023)
Chelsea Mayoh, Jie Mao, Jinhan Xie, Gabor Tax, Shu-Oi Chow, Roxanne Cadiz, Karina Pazaky, Paulette Barahona, Pamela Ajuyah, Peter Trebilcock, Angela Malquori, Kate Gunther, Anica Avila, Doo Young Yun, Stephanie Alfred, Anjana Gopalakrishnan, Alvin Kamili, Marie Wong, Mark J Cowley, Sophie Jessop, Loretta M S Lau, Toby N Trahair, David S Ziegler, Jamie I Fletcher, Andrew J Gifford, Maria Tsoli, Glenn M Marshall, Michelle Haber, Vanessa Tyrrell, Timothy W Failes, Greg M Arndt, Richard B Lock, Paul G Ekert, M Emmy M Dolman
High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer. Cancer research (2023)
Claire E Wakefield, Kate Hetherington, Eden G Robertson, Mark W Donoghoe, Jacqueline D Hunter, Janine Vetsch, Jonathan Michael Marron, Katherine M Tucker, Glenn M Marshall, Alexander Broom, Michelle Haber, Vanessa Tyrrell, David Malkin, Loretta M S Lau, Marion K Mateos, Tracey A O'Brien, David S Ziegler
Hopes, concerns, satisfaction and regret in a precision medicine trial for childhood cancer: a mixed-methods study of parent and patient perspectives. British journal of cancer (2023)
Kate Hetherington, Claire E Wakefield, Kavitha P K Kunalan, Mark W Donoghoe, Brittany C McGill, Joanna E Fardell, Rebecca Daly, Rebecca J Deyell, David S Ziegler
Quality of Life (QoL) of Children and Adolescents Participating in a Precision Medicine Trial for High-Risk Childhood Cancer. Cancers 14 (21) (2022)
Margot A Lazow, Martijn T Nievelstein, Adam Lane, Pratiti Bandopadhayhay, Mariko DeWire-Schottmiller, Maryam Fouladi, John W Glod, Robert J Greiner, Lindsey M Hoffman, Trent R Hummel, Lindsay Kilburn, Sarah Leary, Jane E Minturn, Roger Packer, David S Ziegler, Brooklyn Chaney, Katie Black, Peter de Blank, James L Leach
Volumetric endpoints in diffuse intrinsic pontine glioma: comparison to cross-sectional measures and outcome correlations in the International DIPG/DMG Registry. Neuro-oncology 24 (9) (2022)
Anirban Das, Sumedha Sudhaman, Daniel A Morgenstern, Ailish Coblentz, Jiil Chung, Simone C Stone, Noor Said Alsafwani, Zhihui Amy Liu, Ola Abu Al Karsaneh, Shirin Soleimani, Hagay Ladany, David Chen, Matthew Zatzman, Vanja Cabric, Liana Nobre, Vanessa Bianchi, Melissa Edwards, Lauren C Sambira Nahum, Ayse Bahar Ercan, Arash Nabbi, Shlomi Constantini, Rina Dvir, Michal Yalon-Oren, Gadi Abebe Campino, Shani Caspi, Valerie Larouche, Alyssa Reddy, Michael Osborn, Gary Mason, Scott Lindhorst, Annika Bronsema, Magimairajan Issai Vanan, Enrico Opocher, Rebecca Loret De Mola, Magnus Sabel, Charlotta Frojd, David Sumerauer, David Samuel, Kristina Cole, Stefano Chiaravalli, Maura Massimino, Patrick Tomboc, David S Ziegler, Ben George, An Van Damme, Nobuko Hijiya, David Gass, Rose B McGee, Oz Mordechai, Daniel C Bowers, Theodore W Laetsch, Alexander Lossos, Deborah T Blumenthal, Tomasz Sarosiek, Lee Yi Yen, Jeffrey Knipstein, Anne E Bendel, Lindsey M Hoffman, Sandra Luna-Fineman, Stefanie Zimmermann, Isabelle Scheers, Kim E Nichols, Michal Zapotocky, Jordan R Hansford, John M Maris, Peter B Dirks, Michael D Taylor, Abhaya V Kulkarni, Manohar Shroff, Derek S Tsang, Anita Villani, Wei Xu, Melyssa Aronson, Carol Durno, Adam Shlien, David Malkin, Gad A Getz, Yosef E Maruvka, Pamela S Ohashi, Cynthia Hawkins, Trevor J Pugh, Eric Bouffet, Uri Tabori
Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency. Nature medicine 28 (1) (2022)
Jacqueline D Hunter, Eden G Robertson, Kate Hetherington, David S Ziegler, Glenn M Marshall, Judy Kirk, Jonathan Michael Marron, Avram E Denburg, Kristine Barlow-Stewart, Meera Warby, Katherine M Tucker, Brittany M Lee, Tracey A O'Brien, Claire E Wakefield
What's in a Name? Parents' and Healthcare Professionals' Preferred Terminology for Pathogenic Variants in Childhood Cancer Predisposition Genes. Journal of personalized medicine 12 (8) (2022)
Jessica M Gereis, Kate Hetherington, Lauren Ha, Eden G Robertson, David S Ziegler, Kristine Barlow-Stewart, Katherine M Tucker, Jonathan Michael Marron, Claire E Wakefield
Parents' understanding of genome and exome sequencing for pediatric health conditions: a systematic review. European journal of human genetics : EJHG 30 (11) (2022)
Craig Erker, Adam Lane, Brooklyn Chaney, Sarah E S Leary, Jane E Minturn, Ute Bartels, Roger J Packer, Kathleen Dorris, Nicholas G Gottardo, Katherine E Warren, Alberto Broniscer, W Kieran Mark, Xiaoting Zhu, Peter S White, Phillip Dexheimer, Katie Black, Anthony Asher, Mariko DeWire-Shottmiller, Jordan R Hansford, Sridharan Gururangan, Javad Nazarian, David S Ziegler, Eric Sandler, Lars M Wagner, Carl J Koschmann, Christine Fuller, Rachid Drissi, Blaise V Jones, James Leach, Maryam Fouladi
Characteristics of Patients ≥ 10 Years of Age with Diffuse Intrinsic Pontine Glioma: A Report from the International DIPG Registry. Neuro-oncology (2021)
Aaminah Khan, Laura D Gamble, Dannielle H Upton, Caitlin Ung, Denise M T Yu, Anahid Ehteda, Ruby Pandher, Chelsea Mayoh, Steven Hébert, Nada Jabado, Claudia L Kleinman, Mark R Burns, Murray D Norris, Michelle Haber, Maria Tsoli, David S Ziegler
Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas. Nature communications 12 (1) (2021)
Sumanth Nagabushan, Loretta M S Lau, Paulette Barahona, Marie Wong, Alexandra Sherstyuk, Glenn M Marshall, Vanessa Tyrrell, Eva A Wegner, Paul G Ekert, Mark J Cowley, Chelsea Mayoh, Toby N Trahair, Philip Crowe, Antoinette Anazodo, David S Ziegler
Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor. NPJ precision oncology 5 (1) (2021)
Peter Hau, Didier Frappaz, Elizabeth Hovey, Martin G McCabe, Kristian W Pajtler, Benedikt Wiestler, Clemens Seidel, Stephanie E Combs, Linda Dirven, Martin Klein, Antoinette C Anazodo, Elke Hattingen, Silvia Hofer, Stefan M Pfister, Claus Zimmer, Rolf-Dieter Kortmann, Marie-Pierre Sunyach, Ronan Tanguy, Rachel Effeney, Andreas von Deimling, Felix Sahm, Stefan Rutkowski, Anna S Berghoff, Enrico Franceschi, Estela Pineda Losada, Dagmar Beier, Ellen Peeters, Thierry Gorlia, Maureen Vanlancker, Jacoline E C Bromberg, Julien Gautier, David S Ziegler, Matthias Preusser, Wolfgang Wick, Michael Weller
Development of Randomized Trials in Adults with Medulloblastoma-The Example of EORTC 1634-BTG/NOA-23. Cancers 13 (14) (2021)
Elisha Hayden, Holly Holliday, Rebecca Lehmann, Aaminah Khan, Maria Tsoli, Benjamin S Rayner, David S Ziegler
Therapeutic Targets in Diffuse Midline Gliomas-An Emerging Landscape. Cancers 13 (24) (2021)
Caitlin Ung, Maria Tsoli, Jie Liu, Domenico Cassano, Salvador Pocoví-Martínez, Dannielle H Upton, Anahid Ehteda, Friederike M Mansfeld, Timothy W Failes, Annafranca Farfalla, Christopher Katsinas, Maria Kavallaris, Greg M Arndt, Orazio Vittorio, Giuseppe Cirillo, Valerio Voliani, David S Ziegler
Doxorubicin-Loaded Gold Nanoarchitectures as a Therapeutic Strategy against Diffuse Intrinsic Pontine Glioma. Cancers 13 (6) (2021)
Neevika Manoharan, Pamela Ajuyah, Akanksha Senapati, Marie Wong, Anna Mullins, Michael Rodriguez, Helen Doyle, Geoff McCowage, Loretta M S Lau, Paul G Ekert, David S Ziegler
Diffuse leptomeningeal glioneuronal tumour (DLGNT) in children: the emerging role of genomic analysis. Acta neuropathologica communications 9 (1) (2021)
Rachael L Terry, Deborah Meyran, Emmy D G Fleuren, Chelsea Mayoh, Joe Jiang Zhu, Natacha Omer, David S Ziegler, Michelle Haber, Phillip K Darcy, Joseph A Trapani, Paul J Neeson, Paul G Ekert
Chimeric Antigen Receptor T cell Therapy and the Immunosuppressive Tumor Microenvironment in Pediatric Sarcoma. Cancers 13 (18) (2021)
Loretta M S Lau, Chelsea Mayoh, Jinhan Xie, Paulette Barahona, Karen L MacKenzie, Marie Wong, Alvin Kamili, Maria Tsoli, Tim W Failes, Amit Kumar, Emily V A Mould, Andrew Gifford, Shu-Oi Chow, Mark Pinese, Jamie I Fletcher, Greg M Arndt, Dong-Anh Khuong-Quang, Carol Wadham, Daniel Batey, Georgina Eden, Peter Trebilcock, Swapna Joshi, Stephanie Alfred, Anjana Gopalakrishnan, Aaminah Khan, Dylan Grebert Wade, Patrick A Strong, Elodie Manouvrier, Lisa T Morgan, Miriam Span, Jin Yi Lim, Roxanne Cadiz, Caitlin Ung, David M Thomas, Katherine M Tucker, Meera Warby, Geoffrey B McCowage, Luciano Dalla-Pozza, Jennifer A Byrne, Federica Saletta, Andrew Fellowes, Stephen B Fox, Murray D Norris, Vanessa Tyrrell, Toby N Trahair, Richard B Lock, Mark J Cowley, Paul G Ekert, Michelle Haber, David S Ziegler, Glenn M Marshall
In vitro and in vivo drug screens of tumor cells identify novel therapies for high-risk child cancer. EMBO molecular medicine 14 (4) (2021)
Laura D Gamble, Stefania Purgato, Jayne Murray, Lin Xiao, Denise M T Yu, Kimberley M Hanssen, Federico Manuel Giorgi, Daniel R Carter, Andrew J Gifford, Emanuele Valli, Giorgio Milazzo, Alvin Kamili, Chelsea Mayoh, Bing Liu, Georgina Eden, Sara Sarraf, Sophie Allan, Simone Di Giacomo, Claudia L Flemming, Amanda J Russell, Belamy B Cheung, Andre Oberthuer, Wendy B London, Matthias Fischer, Toby N Trahair, Jamie I Fletcher, Glenn M Marshall, David S Ziegler, Michael D Hogarty, Mark R Burns, Giovanni Perini, Murray D Norris, Michelle Haber
Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma. Science translational medicine 11 (477) (2020)
Marie Wong, Chelsea Mayoh, Loretta M S Lau, Dong Anh K Khoung-Quang, Mark Pinese, Amit Kumar, Paulette Barahona, Emilie E Wilkie, Patricia Sullivan, Rachel Bowen-James, Mustafa H Syed, Iñigo Martincorena, Federico Abascal, Alexandra Sherstyuk, Noemi Auxiliadora Fuentes Bolanos, Jonathan Baber, Peter Priestley, M Emmy M Dolman, Emmy D G Fleuren, Marie-Emilie Gauthier, Emily V A Mould, Velimir Gayevskiy, Andrew J Gifford, Dylan Grebert-Wade, Patrick A Strong, Elodie Manouvrier, Meera Warby, David M Thomas, Judy Kirk, Katherine Tucker, Tracey O'Brien, Frank Alvaro, Geoffry B McCowage, Luciano Dalla-Pozza, Nicholas G Gottardo, Heather Tapp, Paul Wood, Seong-Lin Khaw, Jordan R Hansford, Andrew S Moore, Murray D Norris, Toby N Trahair, Richard B Lock, Vanessa Tyrrell, Michelle Haber, Glenn M Marshall, David S Ziegler, Paul G Ekert, Mark J Cowley
Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer. Nature medicine 26 (11) (2020)
Evadnie Rampersaud, David S Ziegler, Ilaria Iacobucci, Debbie Payne-Turner, Michelle L Churchman, Kasmintan A Schrader, Vijai Joseph, Kenneth Offit, Katherine Tucker, Rosemary Sutton, Meera Warby, Georgia Chenevix-Trench, David G Huntsman, Maria Tsoli, R Scott Mead, Chunxu Qu, Vasiliki Leventaki, Gang Wu, Charles G Mullighan
Germline deletion of ETV6 in familial acute lymphoblastic leukemia. Blood advances 3 (7) (2020)
Jamie I Fletcher, David S Ziegler, Toby N Trahair, Glenn M Marshall, Michelle Haber, Murray D Norris
Too many targets, not enough patients: rethinking neuroblastoma clinical trials. Nature reviews. Cancer 18 (6) (2019)
Eden G Robertson, Claire E Wakefield, Richard J Cohn, Tracey A O'Brien, David S Ziegler, Joanna E Fardell
The Development of Delta: Using Agile to Develop a Decision Aid for Pediatric Oncology Clinical Trial Enrollment. JMIR research protocols 7 (5) (2018)
Weili Sun, Jemily Malvar, Richard Sposto, Anupam Verma, Jennifer J Wilkes, Robyn Dennis, Kenneth Heym, Theodore W Laetsch, Melissa Widener, Susan R Rheingold, Javier Oesterheld, Nobuko Hijiya, Maria Luisa Sulis, Van Huynh, Andrew E Place, Henrique Bittencourt, Raymond Hutchinson, Yoav Messinger, Bill Chang, Yousif Matloub, David S Ziegler, Rebecca Gardner, Todd Cooper, Francesco Ceppi, Michelle Hermiston, Luciano Dalla-Pozza, Kirk R Schultz, Paul Gaynon, Alan S Wayne, James A Whitlock
Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study. Leukemia 32 (11) (2018)