Jamie I Fletcher

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 27

Top Topics

Combination Therapy

Histone Deacetylase

Papillary Thyroid

Top Venues

Nature communications

Cancer research

Science advances

British journal of cancer

This page only lists publications with an associated author ORCID identifier.

Publications

Christopher B Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J Atkinson, Alexander P Sobinoff, Christopher G Tomlinson, Anton Hsu, Robert Lu, Eloise V Dray, Michelle Haber, Jamie I Fletcher, Anthony J Cesare, Rashmi S Hegde, Hilda A Pickett
The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation. Nature communications 15 (1) (2024)
Christopher B Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J Atkinson, Alexander P Sobinoff, Christopher G Tomlinson, Anton Hsu, Robert Lu, Eloise V Dray, Michelle Haber, Jamie I Fletcher, Anthony J Cesare, Rashmi S Hegde, Hilda A Pickett
The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation. Nature communications 15 (1) (2024)
Christopher B Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J Atkinson, Alexander P Sobinoff, Christopher G Tomlinson, Anton Hsu, Robert Lu, Eloise V Dray, Michelle Haber, Jamie I Fletcher, Anthony J Cesare, Rashmi S Hegde, Hilda A Pickett
The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation. Nature communications 15 (1) (2024)
Jayne E Murray, Emanuele Valli, Giorgio Milazzo, Chelsea Mayoh, Andrew J Gifford, Jamie I Fletcher, Chengyuan Xue, Nisitha Jayatilleke, Firoozeh Salehzadeh, Laura D Gamble, Jourdin R C Rouaen, Daniel R Carter, Helen Forgham, Eric O Sekyere, Joanna Keating, Georgina Eden, Sophie Allan, Stephanie Alfred, Frances K Kusuma, Ashleigh Clark, Hannah Webber, Amanda J Russell, Antoine deWeck, Benjamin T Kile, Martina Santulli, Piergiuseppe De Rosa, Emmy D G Fleuren, Weiman Gao, Lorna Wilkinson-White, Jason K K Low, Joel P Mackay, Glenn M Marshall, Douglas J Hilton, Federico Manuel Giorgi, Jan Koster, Giovanni Perini, Michelle Haber, Murray D Norris
The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis. Nature communications 15 (1) (2024)
Christopher B Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J Atkinson, Alexander P Sobinoff, Christopher G Tomlinson, Anton Hsu, Robert Lu, Eloise V Dray, Michelle Haber, Jamie I Fletcher, Anthony J Cesare, Rashmi S Hegde, Hilda A Pickett
The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation. Nature communications 15 (1) (2024)
Christopher B Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J Atkinson, Alexander P Sobinoff, Christopher G Tomlinson, Anton Hsu, Robert Lu, Eloise V Dray, Michelle Haber, Jamie I Fletcher, Anthony J Cesare, Rashmi S Hegde, Hilda A Pickett
The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation. Nature communications 15 (1) (2024)
Jayne E Murray, Emanuele Valli, Giorgio Milazzo, Chelsea Mayoh, Andrew J Gifford, Jamie I Fletcher, Chengyuan Xue, Nisitha Jayatilleke, Firoozeh Salehzadeh, Laura D Gamble, Jourdin R C Rouaen, Daniel R Carter, Helen Forgham, Eric O Sekyere, Joanna Keating, Georgina Eden, Sophie Allan, Stephanie Alfred, Frances K Kusuma, Ashleigh Clark, Hannah Webber, Amanda J Russell, Antoine deWeck, Benjamin T Kile, Martina Santulli, Piergiuseppe De Rosa, Emmy D G Fleuren, Weiman Gao, Lorna Wilkinson-White, Jason K K Low, Joel P Mackay, Glenn M Marshall, Douglas J Hilton, Federico Manuel Giorgi, Jan Koster, Giovanni Perini, Michelle Haber, Murray D Norris
The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis. Nature communications 15 (1) (2024)
Jayne E Murray, Emanuele Valli, Giorgio Milazzo, Chelsea Mayoh, Andrew J Gifford, Jamie I Fletcher, Chengyuan Xue, Nisitha Jayatilleke, Firoozeh Salehzadeh, Laura D Gamble, Jourdin R C Rouaen, Daniel R Carter, Helen Forgham, Eric O Sekyere, Joanna Keating, Georgina Eden, Sophie Allan, Stephanie Alfred, Frances K Kusuma, Ashleigh Clark, Hannah Webber, Amanda J Russell, Antoine deWeck, Benjamin T Kile, Martina Santulli, Piergiuseppe De Rosa, Emmy D G Fleuren, Weiman Gao, Lorna Wilkinson-White, Jason K K Low, Joel P Mackay, Glenn M Marshall, Douglas J Hilton, Federico Manuel Giorgi, Jan Koster, Giovanni Perini, Michelle Haber, Murray D Norris
The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis. Nature communications 15 (1) (2024)
Christopher B Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J Atkinson, Alexander P Sobinoff, Christopher G Tomlinson, Anton Hsu, Robert Lu, Eloise V Dray, Michelle Haber, Jamie I Fletcher, Anthony J Cesare, Rashmi S Hegde, Hilda A Pickett
The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation. Nature communications 15 (1) (2024)
Jordan F Hastings, Sharissa L Latham, Alvin Kamili, Madeleine S Wheatley, Jeremy Z R Han, Marie Wong, Monica Phimmachanh, Max Nobis, Chiara Pantarelli, Antonia L Cadell, Yolande E I O'Donnell, King Ho Leong, Sophie Lynn, Fan-Suo Geng, Lujing Cui, Sabrina Yan, Joanna Achinger-Kawecka, Clare Stirzaker, Murray D Norris, Michelle Haber, Toby N Trahair, Frank Speleman, Katleen De Preter, Mark J Cowley, Ozren Bogdanovic, Paul Timpson, Thomas R Cox, Walter Kolch, Jamie I Fletcher, Dirk Fey, David R Croucher
Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma. Science advances 9 (9) (2023)
Jordan F Hastings, Sharissa L Latham, Alvin Kamili, Madeleine S Wheatley, Jeremy Z R Han, Marie Wong, Monica Phimmachanh, Max Nobis, Chiara Pantarelli, Antonia L Cadell, Yolande E I O'Donnell, King Ho Leong, Sophie Lynn, Fan-Suo Geng, Lujing Cui, Sabrina Yan, Joanna Achinger-Kawecka, Clare Stirzaker, Murray D Norris, Michelle Haber, Toby N Trahair, Frank Speleman, Katleen De Preter, Mark J Cowley, Ozren Bogdanovic, Paul Timpson, Thomas R Cox, Walter Kolch, Jamie I Fletcher, Dirk Fey, David R Croucher
Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma. Science advances 9 (9) (2023)
Jordan F Hastings, Sharissa L Latham, Alvin Kamili, Madeleine S Wheatley, Jeremy Z R Han, Marie Wong, Monica Phimmachanh, Max Nobis, Chiara Pantarelli, Antonia L Cadell, Yolande E I O'Donnell, King Ho Leong, Sophie Lynn, Fan-Suo Geng, Lujing Cui, Sabrina Yan, Joanna Achinger-Kawecka, Clare Stirzaker, Murray D Norris, Michelle Haber, Toby N Trahair, Frank Speleman, Katleen De Preter, Mark J Cowley, Ozren Bogdanovic, Paul Timpson, Thomas R Cox, Walter Kolch, Jamie I Fletcher, Dirk Fey, David R Croucher
Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma. Science advances 9 (9) (2023)
Chelsea Mayoh, Jie Mao, Jinhan Xie, Gabor Tax, Shu-Oi Chow, Roxanne Cadiz, Karina Pazaky, Paulette Barahona, Pamela Ajuyah, Peter Trebilcock, Angela Malquori, Kate Gunther, Anica Avila, Doo Young Yun, Stephanie Alfred, Anjana Gopalakrishnan, Alvin Kamili, Marie Wong, Mark J Cowley, Sophie Jessop, Loretta M S Lau, Toby N Trahair, David S Ziegler, Jamie I Fletcher, Andrew J Gifford, Maria Tsoli, Glenn M Marshall, Michelle Haber, Vanessa Tyrrell, Timothy W Failes, Greg M Arndt, Richard B Lock, Paul G Ekert, M Emmy M Dolman
High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer. Cancer research (2023)
Janith A Seneviratne, Daniel R Carter, Rituparna Mittra, Andrew Gifford, Patrick Y Kim, Jie-Si Luo, Chelsea Mayoh, Alice Salib, Aldwin S Rahmanto, Jayne Murray, Ngan C Cheng, Zsuzsanna Nagy, Qian Wang, Ane Kleynhans, Owen Tan, Selina K Sutton, Chengyuan Xue, Sylvia A Chung, Yizhuo Zhang, Chengtao Sun, Li Zhang, Michelle Haber, Murray D Norris, Jamie I Fletcher, Tao Liu, Pierre J Dilda, Philip J Hogg, Belamy B Cheung, Glenn M Marshall
Inhibition of mitochondrial translocase SLC25A5 and histone deacetylation is an effective combination therapy in neuroblastoma. International journal of cancer (2022)
Kimberley M Hanssen, Madeleine S Wheatley, Denise M T Yu, Gwenaëlle Conseil, Murray D Norris, Michelle Haber, Susan P C Cole, Jamie I Fletcher
GSH facilitates the binding and inhibitory activity of novel multidrug resistance protein 1 (MRP1) modulators. The FEBS journal 289 (13) (2022)
Vinod Vijay Subhash, Libby Huang, Alvin Kamili, Marie Wong, Dan Chen, Nicola C Venn, Caroline Atkinson, Chelsea Mayoh, Pooja Venkat, Vanessa Tyrrell, Glenn M Marshall, Mark J Cowley, Paul G Ekert, Murray D Norris, Michelle Haber, Michelle J Henderson, Rosemary Sutton, Jamie I Fletcher, Toby N Trahair
Whole-genome sequencing facilitates patient-specific quantitative PCR-based minimal residual disease monitoring in acute lymphoblastic leukaemia, neuroblastoma and Ewing sarcoma. British journal of cancer (2021)
Lin Xiao, Klaartje Somers, Jayne E Murray, Ruby Pandher, Mawar Karsa, Emma Ronca, Angelika Bongers, Rachael L Terry, Anahid Ehteda, Laura D Gamble, Natalia Issaeva, Katerina I Leonova, Aisling O'Connor, Chelsea Mayoh, Pooja Venkat, Hazel Q Y Quek, Jennifer Brand, Frances K Kusuma, Jessica A Pettitt, Erin Mosmann, Adam Kearns, Georgina Eden, Stephanie Alfred, Sophie Allan, Lei Zhai, Alvin Kamili, Andrew J Gifford, Daniel R Carter, Michelle J Henderson, Jamie I Fletcher, Glenn Marshall, Ricky W Johnstone, Anthony J Cesare, David S Ziegler, Andrei V Gudkov, Katerina V Gurova, Murray D Norris, Michelle Haber
Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (15) (2021)
Loretta M S Lau, Chelsea Mayoh, Jinhan Xie, Paulette Barahona, Karen L MacKenzie, Marie Wong, Alvin Kamili, Maria Tsoli, Tim W Failes, Amit Kumar, Emily V A Mould, Andrew Gifford, Shu-Oi Chow, Mark Pinese, Jamie I Fletcher, Greg M Arndt, Dong-Anh Khuong-Quang, Carol Wadham, Daniel Batey, Georgina Eden, Peter Trebilcock, Swapna Joshi, Stephanie Alfred, Anjana Gopalakrishnan, Aaminah Khan, Dylan Grebert Wade, Patrick A Strong, Elodie Manouvrier, Lisa T Morgan, Miriam Span, Jin Yi Lim, Roxanne Cadiz, Caitlin Ung, David M Thomas, Katherine M Tucker, Meera Warby, Geoffrey B McCowage, Luciano Dalla-Pozza, Jennifer A Byrne, Federica Saletta, Andrew Fellowes, Stephen B Fox, Murray D Norris, Vanessa Tyrrell, Toby N Trahair, Richard B Lock, Mark J Cowley, Paul G Ekert, Michelle Haber, David S Ziegler, Glenn M Marshall
In vitro and in vivo drug screens of tumor cells identify novel therapies for high-risk child cancer. EMBO molecular medicine 14 (4) (2021)
Clarissa E Schilstra, Ursula Margaret Sansom-Daly, Maria Schaffer, Joanna E Fardell, Antoinette C Anazodo, Geoffrey B McCowage, Jamie I Fletcher, Glenn M Marshall, Jennifer Buchhorn-White, Michael Evtushenko, Toby N Trahair, Sarah J Ellis
"We Have All This Knowledge to Give, So Use Us as a Resource": Partnering with Adolescent and Young Adult Cancer Survivors to Determine Consumer-Led Research Priorities. Journal of adolescent and young adult oncology (2021)
Christoph Grohmann, Francesca Walker, Mark Devlin, Meng-Xiao Luo, Anderly C Chüeh, Judy Doherty, François Vaillant, Gwo-Yaw Ho, Matthew J Wakefield, Clare E Weeden, Alvin Kamili, Jayne Murray, Sela T Po'uha, Janet Weinstock, Serena R Kane, Maree C Faux, Esmee Broekhuizen, Ye Zheng, Kristy Shield-Artin, Nadia J Kershaw, Chin Wee Tan, Helen M Witchard, Gregor Ebert, Susan A Charman, Ian Street, Maria Kavallaris, Michelle Haber, Jamie I Fletcher, Marie-Liesse Asselin-Labat, Clare L Scott, Jane E Visvader, Geoffrey J Lindeman, Keith G Watson, Antony W Burgess, Guillaume L Lessene
Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors. Cell death & disease 12 (3) (2021)
Ashleigh M Fordham, Jinhan Xie, Andrew J Gifford, Carol Wadham, Lisa T Morgan, Emily V A Mould, Mitali Fadia, Lei Zhai, Hassina Massudi, Zara S Ali, Glenn M Marshall, Robyn E Lukeis, Jamie I Fletcher, Karen L MacKenzie, Toby N Trahair
CD30 and ALK combination therapy has high therapeutic potency in RANBP2-ALK-rearranged epithelioid inflammatory myofibroblastic sarcoma. British journal of cancer 123 (7) (2020)
Alvin Kamili, Andrew J Gifford, Nancy Li, Chelsea Mayoh, Shu-Oi Chow, Timothy W Failes, Georgina L Eden, Roxanne Cadiz, Jinhan Xie, Robyn E Lukeis, Murray D Norris, Michelle Haber, Geoffrey B McCowage, Greg M Arndt, Toby N Trahair, Jamie I Fletcher
Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy. British journal of cancer 122 (5) (2020)
Jingwei Chen, Christopher Nelson, Matthew Wong, Andrew E Tee, Pei Y Liu, Ting La, Jamie I Fletcher, Alvin Kamili, Chelsea Mayoh, Christoph Bartenhagen, Toby N Trahair, Ning Xu, Nisitha Jayatilleke, Marie Wong, Hui Peng, Bernard Atmadibrata, Belamy B Cheung, Qing Lan, Tracy M Bryan, Pieter Mestdagh, Jo Vandesompele, Valerie Combaret, Valentina Boeva, Jenny Yingzi Wang, Isabelle Janoueix-Lerosey, Mark J Cowley, Karen L MacKenzie, Alla Dolnikov, Jinyan Li, Patsie Polly, Glenn M Marshall, Roger R Reddel, Murray D Norris, Michelle Haber, Matthias Fischer, Yuan Yuan Zhang, Hilda A Pickett, Tao Liu
Targeted Therapy of TERT-Rearranged Neuroblastoma with BET Bromodomain Inhibitor and Proteasome Inhibitor Combination Therapy. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (5) (2020)
Alvin Kamili, Caroline Atkinson, Toby N Trahair, Jamie I Fletcher
Mouse models of high-risk neuroblastoma. Cancer metastasis reviews 39 (1) (2020)
Andrew E Tee, Olivia C Ciampa, Matthew Wong, Jamie I Fletcher, Alvin Kamili, Jingwei Chen, Nicholas Ho, Yuting Sun, Daniel R Carter, Belamy B Cheung, Glenn M Marshall, Pei Y Liu, Tao Liu
Combination therapy with the CDK7 inhibitor and the tyrosine kinase inhibitor exerts synergistic anticancer effects against MYCN-amplified neuroblastoma. International journal of cancer 147 (7) (2020)
Jixuan Gao, MoonSun Jung, Chelsea Mayoh, Pooja Venkat, Katherine M Hannan, Jamie I Fletcher, Alvin Kamili, Andrew J Gifford, Eric P Kusnadi, Richard B Pearson, Ross D Hannan, Michelle Haber, Murray D Norris, Klaartje Somers, Michelle J Henderson
Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC-Driven Cancer Progression. Cancer research 80 (17) (2020)
Jessica Koach, Jessica K Holien, Hassina Massudi, Daniel R Carter, Olivia C Ciampa, Mika Herath, Taylor Lim, Janith A Seneviratne, Giorgio Milazzo, Jayne E Murray, Joshua A McCarroll, Bing Liu, Chelsea Mayoh, Bryce Keenan, Brendan W Stevenson, Michael A Gorman, Jessica Lilian Bell, Larissa Doughty, Stefan Hüttelmaier, Andre Oberthuer, Matthias Fischer, Andrew J Gifford, Tao Liu, Xiaoling Zhang, Shizhen Zhu, W Clay Gustafson, Michelle Haber, Murray D Norris, Jamie I Fletcher, Giovanni Perini, Michael W Parker, Belamy B Cheung, Glenn M Marshall
Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface. Cancer research 79 (21) (2019)