Characterisation of endogenous Claudin-1 expression, motility and susceptibility to hepatitis C virus in CRISPR knock-in cells.
Camille M H ClémentMaika S DeffieuCristina M DorobantuThomas F BaumertNilda Vanesa Ayala-NunezYves MélyPhilippe RondeRaphaël GaudinPublished in: Biology of the cell (2020)
Although HCV-related studies may not be achieved with these cells, our work provides a novel tool to study the cell biology of TJ-associated proteins and a potential screening strategy measuring CLDN1 expression levels.
Keyphrases
- hepatitis c virus
- induced apoptosis
- poor prognosis
- cell cycle arrest
- human immunodeficiency virus
- endoplasmic reticulum stress
- single cell
- crispr cas
- escherichia coli
- binding protein
- signaling pathway
- staphylococcus aureus
- genome editing
- biofilm formation
- gene expression
- long non coding rna
- hiv infected
- human health