Protodioscin Induces Mitochondrial Apoptosis of Human Hepatocellular Carcinoma Cells Through Eliciting ER Stress-Mediated IP3R Targeting Mfn1/Bak Expression.

Chen-Lin YuHsiang-Lin LeeChiao-Wen LinShih-Wei WangChing-Pin LinYi-Hsien HsiehHui-Ling Chiou

Published in: Journal of hepatocellular carcinoma (2022)

Our study sheds light on the understanding of the anti-HCC effects of PD and may open new aspects for the development of novel treatment for human hepatocellular carcinoma.

Keyphrases

endothelial cells
oxidative stress
induced pluripotent stem cells
poor prognosis
pluripotent stem cells
minimally invasive
cell death
endoplasmic reticulum stress
cell cycle arrest
replacement therapy