IL-13 Regulates Orai1 Expression in Human Bronchial Smooth Muscle Cells and Airway Remodeling in Asthma Mice Model via LncRNA H19.

Lin-Li XiangQian-Qian WanYi-Min WangShao-Jun HeWen-Juan XuMei DingJin-Jin ZhangYuan-Li SunXiang DongYing ZhouYu-Bao Cui Ya-Dong Gao

Published in: Journal of asthma and allergy (2022)

H19 may mediate the effects of IL-13 on Orai1 expression by inhibition of miR-93-5p in hBSMCs. H19 may be a therapeutic target for airway inflammation and airway remodeling.

Keyphrases

poor prognosis
endothelial cells
long non coding rna
chronic obstructive pulmonary disease
lung function
metabolic syndrome
long noncoding rna
pluripotent stem cells
allergic rhinitis