Glucose-mediated insulin secretion is improved in FHL2-deficient mice and elevated FHL2 expression in humans is associated with type 2 diabetes.
Jayron J HabibeMaria P Clemente-OlivoTorsten P M ScheithauerElena RampanelliHilde J HerremaMariska VosArnout MieremetMax NieuwdorpDaniel H van RaalteEtto C EringaCarlie J M de VriesPublished in: Diabetologia (2022)
The human islet microarray datasets used are publicly available and can be found on https://www.ncbi.nlm.nih.gov/geo/ .