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First-in-human phase I study of immunomodulatory E7046, an antagonist of PGE2-receptor E-type 4 (EP4), in patients with advanced cancers.

David S HongAparna ParikhGeoffrey I ShapiroAndrea VargaAung NaingFunda Meric-BernstamÖzlem AtamanLarisa ReydermanTerri A BinderMin RenMingjie LiuSatish DayalAmy Y SiuPallavi SachdevLucy XuVijay Bhagawati-PrasadIlian TchakovChean Eng OoiXingfeng BaoAurélien Marabelle
Published in: Journal for immunotherapy of cancer (2021)
NCT02540291.
Keyphrases
  • endothelial cells
  • pluripotent stem cells
  • young adults