Preparatory phase for clinical trials of COVID-19 vaccine in Nepal.
Govind Prasad GuptaYogendra ShahDhan Kumar PantSunil LekhakRamesh ShahiAnanda MandalPramod PoudelShayam Prakash DumreKishor PandeyBasu Dev PandeyPublished in: Human vaccines & immunotherapeutics (2020)
Public health data suggested a rapid rise in COVID-19-confirmed cases in Nepal along with increased deaths. There has been a wide variation in clinical outcomes of this disease. Control of this pandemic depends on the availability of vaccines or drugs for SARS-CoV-2. Thus, viral and human genetics/genomics and immunology are necessary to understand whether these factors will affect clinical trials of vaccines in Nepal.
Keyphrases
- sars cov
- clinical trial
- public health
- tertiary care
- respiratory syndrome coronavirus
- coronavirus disease
- endothelial cells
- phase ii
- single cell
- open label
- electronic health record
- big data
- study protocol
- induced pluripotent stem cells
- randomized controlled trial
- phase iii
- double blind
- loop mediated isothermal amplification
- drug induced
- quantum dots
- global health