Exposure to blue light stimulates the proangiogenic capability of exosomes derived from human umbilical cord mesenchymal stem cells.

Kun YangDong LiMeitian WangZhiliang XuXiao ChenQiao LiuWenjie SunJiangxia LiYaoqin GongDuo LiuChangshun ShaoQiji LiuXi Li

Published in: Stem cell research & therapy (2019)

Blue (455 nm) light illumination improved the therapeutic effects of hUC-MSC exosomes by enhancing their proangiogenic ability in vitro and in vivo with the upregulation of the following two miRNAs: miR-135b-5p and miR-499a-3p.

Keyphrases

mesenchymal stem cells
umbilical cord
light emitting
endothelial cells
bone marrow
cell therapy
induced pluripotent stem cells
photodynamic therapy
cell proliferation
poor prognosis
signaling pathway
pluripotent stem cells
stem cells