Associations of OSA and Nocturnal Hypoxemia with Strength and Body Composition in Community Dwelling Middle Aged and Older Men.
David James StevensSarah L AppletonAndrew D VincentYohannes Adama MelakuSean MartinTiffany K GillCatherine L HillAndrew VakulinRobert J AdamsGary Allen WittertPublished in: Nature and science of sleep (2020)
Our findings suggest impairments in HGS may be related to fat infiltration of muscle, hypoxemia-induced reductions in peripheral neural innervation, or even endothelial dysfunction, which is a common outcome of hypoxemia. Longitudinal data are needed to further examine these hypotheses and establish if reduced grip strength in patients with OSA is associated with long-term adverse health outcomes.
Keyphrases
- community dwelling
- body composition
- obstructive sleep apnea
- resistance training
- bone mineral density
- positive airway pressure
- high glucose
- adipose tissue
- middle aged
- skeletal muscle
- diabetic rats
- blood pressure
- drug induced
- sleep apnea
- electronic health record
- big data
- fatty acid
- physical activity
- cross sectional
- sleep quality
- endothelial cells
- depressive symptoms
- adverse drug
- artificial intelligence
- deep learning