ToxNav germline genetic testing and PROMinet digital mobile application toxicity monitoring: Results of a prospective single-center clinical utility study-PRECISE study.
Lennard Y W LeeThomas StarkeyShivan SivakumarSusan FotheringhamGuy MozolowskiVanessa ShearwoodClaire PallesPhilip CamilleriDavid N ChurchRachel KerrDavid KerrPublished in: Cancer medicine (2019)
The PRECISE clinical trial demonstrated that a germline DNA sequencing-based test can provide clinically relevant information to alter clinicians' fluoropyrimidine prescription. The study also obtained high volume, high granularity patient-reported toxicity data that might allow the improvement and personalization of chemotherapy management.