David N Church (David Church)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 29

Top Topics

Squamous Cell Carcinoma

Endometrial Cancer

Top Venues

Nature medicine

The Journal of pathology

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

The journal of pathology. Clinical research

This page only lists publications with an associated author ORCID identifier.

Publications

Enric Domingo, Caroline A Kelly, Jennifer Hay, Owen Sansom, Noori Maka, Karin Oien, Timothy J Iveson, Mark Saunders, Rachel Kerr, Ian Tomlinson, Joanne Edwards, Andrea Harkin, Marta Nowak, Viktor Hendrik Koelzer, Alistair Easton, Ioannis Boukovinas, Eleni Moustou, Ippokratis Messaritakis, Maria Chondrozoumaki, Michaela Karagianni, Franck Pagès, Fanny Arnoux, Christelle Lautard, Yoann Lovera, Isabelle Boquet, Aurelie Catteau, Jerome Galon, null null, Ioannis Souglakos, David N Church
Prognostic and Predictive Value of Immunoscore in Stage III Colorectal Cancer: Pooled Analysis of Cases From the SCOT and IDEA-HORG Studies. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (18) (2024)
Alex J Cornish, Andreas J Gruber, Ben Kinnersley, Daniel Chubb, Anna Frangou, Giulio Caravagna, Boris Noyvert, Eszter Lakatos, Henry M Wood, Steve Thorn, Richard Culliford, Claudia Arnedo-Pac, Jacob Househam, William Cross, Amit Sud, Philip J Law, Maire Ni Leathlobhair, Aliah Hawari, Connor Woolley, Kitty Sherwood, Nathalie Feeley, Güler Gül, Juan Fernandez-Tajes, Luis Zapata, Ludmil B Alexandrov, Nirupa Murugaesu, Alona Sosinsky, Jonathan Mitchell, Núria López-Bigas, Philip Quirke, David N Church, Ian P M Tomlinson, Andrea Sottoriva, Trevor A Graham, David C Wedge, Richard S Houlston
The genomic landscape of 2,023 colorectal cancers. Nature (2024)
Alex J Cornish, Andreas J Gruber, Ben Kinnersley, Daniel Chubb, Anna Frangou, Giulio Caravagna, Boris Noyvert, Eszter Lakatos, Henry M Wood, Steve Thorn, Richard Culliford, Claudia Arnedo-Pac, Jacob Househam, William Cross, Amit Sud, Philip J Law, Maire Ni Leathlobhair, Aliah Hawari, Connor Woolley, Kitty Sherwood, Nathalie Feeley, Güler Gül, Juan Fernandez-Tajes, Luis Zapata, Ludmil B Alexandrov, Nirupa Murugaesu, Alona Sosinsky, Jonathan Mitchell, Núria López-Bigas, Philip Quirke, David N Church, Ian P M Tomlinson, Andrea Sottoriva, Trevor A Graham, David C Wedge, Richard S Houlston
The genomic landscape of 2,023 colorectal cancers. Nature (2024)
Enric Domingo, Caroline A Kelly, Jennifer Hay, Owen Sansom, Noori Maka, Karin Oien, Timothy J Iveson, Mark Saunders, Rachel Kerr, Ian Tomlinson, Joanne Edwards, Andrea Harkin, Marta Nowak, Viktor Hendrik Koelzer, Alistair Easton, Ioannis Boukovinas, Eleni Moustou, Ippokratis Messaritakis, Maria Chondrozoumaki, Michaela Karagianni, Franck Pagès, Fanny Arnoux, Christelle Lautard, Yoann Lovera, Isabelle Boquet, Aurelie Catteau, Jerome Galon, null null, Ioannis Souglakos, David N Church
Prognostic and Predictive Value of Immunoscore in Stage III Colorectal Cancer: Pooled Analysis of Cases From the SCOT and IDEA-HORG Studies. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Anneke L Eerkens, Koen Brummel, Annegé Vledder, Sterre T Paijens, Marta Requesens, Dominik Loiero, Nienke van Rooij, Annechien Plat, Floris-Jan Haan, Patty Klok, Refika Yigit, Thijs Roelofsen, Natascha M de Lange, Rie Klomp, David N Church, Arja Ter Elst, Rene Wardenaar, Diana Carolina Johanna Spierings, Floris Foijer, Viktor Hendrik Koelzer, Tjalling Bosse, Joost Bart, Mathilde Jalving, Anna K L Reyners, Marco de Bruyn, Hans W Nijman
Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study. Nature communications 15 (1) (2024)
Enric Domingo, Caroline A Kelly, Jennifer Hay, Owen Sansom, Noori Maka, Karin Oien, Timothy J Iveson, Mark Saunders, Rachel Kerr, Ian Tomlinson, Joanne Edwards, Andrea Harkin, Marta Nowak, Viktor Hendrik Koelzer, Alistair Easton, Ioannis Boukovinas, Eleni Moustou, Ippokratis Messaritakis, Maria Chondrozoumaki, Michaela Karagianni, Franck Pagès, Fanny Arnoux, Christelle Lautard, Yoann Lovera, Isabelle Boquet, Aurelie Catteau, Jerome Galon, null null, Ioannis Souglakos, David N Church
Prognostic and Predictive Value of Immunoscore in Stage III Colorectal Cancer: Pooled Analysis of Cases From the SCOT and IDEA-HORG Studies. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (18) (2024)
Anneke L Eerkens, Koen Brummel, Annegé Vledder, Sterre T Paijens, Marta Requesens, Dominik Loiero, Nienke van Rooij, Annechien Plat, Floris-Jan Haan, Patty Klok, Refika Yigit, Thijs Roelofsen, Natascha M de Lange, Rie Klomp, David N Church, Arja Ter Elst, Rene Wardenaar, Diana Carolina Johanna Spierings, Floris Foijer, Viktor Hendrik Koelzer, Tjalling Bosse, Joost Bart, Mathilde Jalving, Anna K L Reyners, Marco de Bruyn, Hans W Nijman
Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study. Nature communications 15 (1) (2024)
Enric Domingo, Caroline A Kelly, Jennifer Hay, Owen Sansom, Noori Maka, Karin Oien, Timothy J Iveson, Mark Saunders, Rachel Kerr, Ian Tomlinson, Joanne Edwards, Andrea Harkin, Marta Nowak, Viktor Hendrik Koelzer, Alistair Easton, Ioannis Boukovinas, Eleni Moustou, Ippokratis Messaritakis, Maria Chondrozoumaki, Michaela Karagianni, Franck Pagès, Fanny Arnoux, Christelle Lautard, Yoann Lovera, Isabelle Boquet, Aurelie Catteau, Jerome Galon, null null, Ioannis Souglakos, David N Church
Prognostic and Predictive Value of Immunoscore in Stage III Colorectal Cancer: Pooled Analysis of Cases From the SCOT and IDEA-HORG Studies. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (18) (2024)
Matthew Brown, Alicia Leon, Katarzyna Kedzierska, Charlotte Moore, Hayley L Belnoue-Davis, Susanne Flach, John P Lydon, Francesco J DeMayo, Annabelle Lewis, Tjalling Bosse, Ian Tomlinson, David N Church
Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis. EMBO molecular medicine (2023)
Benjamin R Challoner, Andrew Woolston, David Lau, Marta Buzzetti, Caroline Fong, Louise J Barber, Gayathri Anandappa, Richard Crux, Ioannis Assiotis, Kerry Fenwick, Ruwaida Begum, Dipa Begum, Tom Lund, Nanna Sivamanoharan, Harold B Sansano, Melissa Domingo-Arada, Amina Tran, Hardev Pandha, David N Church, Bryony Eccles, Richard Ellis, Stephen Falk, Mark Hill, Daniel Krell, Nirupa Murugaesu, Luke Nolan, Vanessa Potter, Mark Saunders, Kai-Keen Shiu, Sebastian Guettler, James L Alexander, Héctor Lázare-Iglesias, James Kinross, Jamie Murphy, Katharina von Loga, David Cunningham, Ian Chau, Naureen Starling, Juan Ruiz-Bañobre, Tony Dhillon, Marco Gerlinger
Genetic and immune landscape evolution in MMR-deficient colorectal cancer. The Journal of pathology (2023)
Anja L Frei, Anthony McGuigan, Ritik Rak Sinha, Mark A Glaire, Faiz Jabbar, Luciana Gneo, Tijana Tomasevic, Andrea Harkin, Tim J Iveson, Mark Saunders, Karin Oein, Noori Maka, Francesco Pezella, Leticia Campo, Jennifer Hay, Joanne Edwards, Owen James Sansom, Caroline Kelly, Ian Tomlinson, Wanja Kildal, Rachel S Kerr, David J Kerr, Håvard E Danielsen, Enric Domingo, null null, David N Church, Viktor Hendrik Koelzer
Accounting for intensity variation in image analysis of large-scale multiplexed clinical trial datasets. The journal of pathology. Clinical research (2023)
Mark A Glaire, Neil Aj Ryan, Marieke E Ijsselsteijn, Katarzyna Kedzierska, Sofia Obolenski, Reem Ali, Emma J Crosbie, Tjalling Bosse, Noel Fcc de Miranda, David N Church
Discordant prognosis of mismatch repair deficiency in colorectal and endometrial cancer reflects variation in antitumour immune response and immune escape. The Journal of pathology 257 (3) (2022)
Chelsea Alice Taylor, Robert A Watson, Orion Tong, Weiyu Ye, Isar Nassiri, James J Gilchrist, Alba Verge de Los Aires, Piyush Kumar Sharma, Surya Koturan, Rosalin A Cooper, Victoria K Woodcock, Elsita Jungkurth, Brian Shine, Nicholas Coupe, Miranda J Payne, David N Church, Vivek Naranbhai, Stefan Groha, Paul Emery, Kulveer Mankia, Matthew L Freedman, Toni K Choueiri, Mark Ross Middleton, Alexander Gusev, Benjamin P Fairfax
IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma. Nature medicine (2022)
Chelsea Alice Taylor, Robert A Watson, Orion Tong, Weiyu Ye, Isar Nassiri, James J Gilchrist, Alba Verge de Los Aires, Piyush Kumar Sharma, Surya Koturan, Rosalin A Cooper, Victoria K Woodcock, Elsita Jungkurth, Brian Shine, Nicholas Coupe, Miranda J Payne, David N Church, Vivek Naranbhai, Stefan Groha, Paul Emery, Kulveer Mankia, Matthew L Freedman, Toni K Choueiri, Mark Ross Middleton, Alexander Gusev, Benjamin P Fairfax
IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma. Nature medicine 28 (12) (2022)
Chelsea Alice Taylor, Robert A Watson, Orion Tong, Weiyu Ye, Isar Nassiri, James J Gilchrist, Alba Verge de Los Aires, Piyush Kumar Sharma, Surya Koturan, Rosalin A Cooper, Victoria K Woodcock, Elsita Jungkurth, Brian Shine, Nicholas Coupe, Miranda J Payne, David N Church, Vivek Naranbhai, Stefan Groha, Paul Emery, Kulveer Mankia, Matthew L Freedman, Toni K Choueiri, Mark Ross Middleton, Alexander Gusev, Benjamin P Fairfax
IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma. Nature medicine 28 (12) (2022)
Chelsea Alice Taylor, Robert A Watson, Orion Tong, Weiyu Ye, Isar Nassiri, James J Gilchrist, Alba Verge de Los Aires, Piyush Kumar Sharma, Surya Koturan, Rosalin A Cooper, Victoria K Woodcock, Elsita Jungkurth, Brian Shine, Nicholas Coupe, Miranda J Payne, David N Church, Vivek Naranbhai, Stefan Groha, Paul Emery, Kulveer Mankia, Matthew L Freedman, Toni K Choueiri, Mark Ross Middleton, Alexander Gusev, Benjamin P Fairfax
IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma. Nature medicine 28 (12) (2022)
Chelsea Alice Taylor, Robert A Watson, Orion Tong, Weiyu Ye, Isar Nassiri, James J Gilchrist, Alba Verge de Los Aires, Piyush Kumar Sharma, Surya Koturan, Rosalin A Cooper, Victoria K Woodcock, Elsita Jungkurth, Brian Shine, Nicholas Coupe, Miranda J Payne, David N Church, Vivek Naranbhai, Stefan Groha, Paul Emery, Kulveer Mankia, Matthew L Freedman, Toni K Choueiri, Mark Ross Middleton, Alexander Gusev, Benjamin P Fairfax
IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma. Nature medicine 28 (12) (2022)
Chelsea Alice Taylor, Robert A Watson, Orion Tong, Weiyu Ye, Isar Nassiri, James J Gilchrist, Alba Verge de Los Aires, Piyush Kumar Sharma, Surya Koturan, Rosalin A Cooper, Victoria K Woodcock, Elsita Jungkurth, Brian Shine, Nicholas Coupe, Miranda J Payne, David N Church, Vivek Naranbhai, Stefan Groha, Paul Emery, Kulveer Mankia, Matthew L Freedman, Toni K Choueiri, Mark Ross Middleton, Alexander Gusev, Benjamin P Fairfax
IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma. Nature medicine 28 (12) (2022)
Chelsea Alice Taylor, Robert A Watson, Orion Tong, Weiyu Ye, Isar Nassiri, James J Gilchrist, Alba Verge de Los Aires, Piyush Kumar Sharma, Surya Koturan, Rosalin A Cooper, Victoria K Woodcock, Elsita Jungkurth, Brian Shine, Nicholas Coupe, Miranda J Payne, David N Church, Vivek Naranbhai, Stefan Groha, Paul Emery, Kulveer Mankia, Matthew L Freedman, Toni K Choueiri, Mark Ross Middleton, Alexander Gusev, Benjamin P Fairfax
IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma. Nature medicine 28 (12) (2022)
Matteo Morotti, Ashwag Albukhari, Abdulkhaliq Alsaadi, Mara Artibani, James D Brenton, Stuart M Curbishley, Tao Dong, Michael L Dustin, Zhiyuan Hu, Nicholas McGranahan, Martin L Miller, Laura Santana-Gonzalez, Leonard W Seymour, Tingyan Shi, Peter Van Loo, Christopher Yau, Helen White, Nina Wietek, David N Church, David C Wedge, Ahmed A Ahmed
Promises and challenges of adoptive T-cell therapies for solid tumours. British journal of cancer 124 (11) (2021)
Alicia Léon-Castillo, Ester Gilvazquez, Remi Nout, Vincent Thbm Smit, Jessica N McAlpine, Melissa McConechy, Stefan Kommoss, Sara Y Brucker, Joseph W Carlson, Elisabeth Epstein, Tilman T Rau, Robert A Soslow, Raji Ganesan, Xavier Matias-Guiu, Esther Oliva, Beth T Harrison, David N Church, C Blake Gilks, Tjalling Bosse
Clinicopathological and molecular characterisation of 'multiple-classifier' endometrial carcinomas. The Journal of pathology 250 (3) (2020)
Nanda Horeweg, Marco de Bruyn, Remi A Nout, Ellen Stelloo, Katarzyna Kedziersza, Alicia Léon-Castillo, Annechien Plat, Kirsten D Mertz, Michelle Osse, Ina M Jürgenliemk-Schulz, Ludy C H W Lutgens, Jan J Jobsen, Elzbieta M van der Steen-Banasik, Vincent T Smit, Carien L Creutzberg, Tjalling Bosse, Hans W Nijman, Viktor Hendrik Koelzer, David N Church
Prognostic Integrated Image-Based Immune and Molecular Profiling in Early-Stage Endometrial Cancer. Cancer immunology research 8 (12) (2020)
Alicia Léon-Castillo, Heidi Britton, Melissa K McConechy, Jessica N McAlpine, Remi Nout, Stefan Kommoss, Sara Y Brucker, Joseph W Carlson, Elisabeth Epstein, Tilman T Rau, Tjalling Bosse, David N Church, C Blake Gilks
Interpretation of somatic POLE mutations in endometrial carcinoma. The Journal of pathology 250 (3) (2020)
Peter G Alexander, Antonia K Roseweir, Kathryn A F Pennel, Hester C van Wyk, Arfon Gethyn Morgan Tregellis Powell, Donald C McMillan, Paul G Horgan, Caroline Kelly, Jennifer Hay, Owen Sansom, Andrea Harkin, Campbell S D Roxburgh, Janet Graham, David N Church, Ian P M Tomlinson, Mark Saunders, Tim J Iveson, Joanne Edwards, James Hugh Park
The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer. British journal of cancer 124 (4) (2020)
Antonia K Roseweir, James Hugh Park, Sanne Ten Hoorn, Arfon Gmt Powell, Susan Aherne, Campbell Sd Roxburgh, Donald C McMillan, Paul G Horgan, Elizabeth Ryan, Kieran Sheahan, Louis Vermeulen, James Paul, Andrea Harkin, Janet Graham, Owen J Sansom, David N Church, Ian Tomlinson, Mark Saunders, Tim J Iveson, Joanne Edwards
Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer. The journal of pathology. Clinical research 6 (4) (2020)
Hagma H Workel, Joyce M Lubbers, Roland Arnold, Thalina M Prins, Pieter van der Vlies, Kim de Lange, Tjalling Bosse, Inge C van Gool, Florine A Eggink, Maartje C A Wouters, Fenne L Komdeur, Elisabeth C van der Slikke, Carien L Creutzberg, Arjan Kol, Annechien Plat, Mark Glaire, David N Church, Hans W Nijman, Marco de Bruyn
A Transcriptionally Distinct CXCL13+CD103+CD8+ T-cell Population Is Associated with B-cell Recruitment and Neoantigen Load in Human Cancer. Cancer immunology research 7 (5) (2019)
Lennard Y W Lee, Thomas Starkey, Shivan Sivakumar, Susan Fotheringham, Guy Mozolowski, Vanessa Shearwood, Claire Palles, Philip Camilleri, David N Church, Rachel Kerr, David Kerr
ToxNav germline genetic testing and PROMinet digital mobile application toxicity monitoring: Results of a prospective single-center clinical utility study-PRECISE study. Cancer medicine 8 (14) (2019)
Daniel Temko, Inge C Van Gool, Emily Rayner, Mark Glaire, Seiko Makino, Matthew Brown, Laura Chegwidden, Claire Palles, Jeroen Depreeuw, Andrew D Beggs, Chaido Stathopoulou, John Mason, Ann-Marie Baker, Marc Williams, Vincenzo Cerundolo, Margarida Rei, Jenny C Taylor, Anna Schuh, Ahmed Ahmed, Frédéric Amant, Diether Lambrechts, Vincent Thbm Smit, Tjalling Bosse, Trevor A Graham, David N Church, Ian Tomlinson
Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response. The Journal of pathology 245 (3) (2018)
Inge C Van Gool, Ellen Stelloo, Remi A Nout, Hans W Nijman, Richard J Edmondson, David N Church, Helen J MacKay, Alexandra Leary, Melanie E Powell, Linda Mileshkin, Carien L Creutzberg, Vincent T H B M Smit, Tjalling Bosse
Prognostic significance of L1CAM expression and its association with mutant p53 expression in high-risk endometrial cancer. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 29 (2) (2016)