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Age-Related Macular Degeneration in an Ageing Society - Current Epidemiological Research.

Caroline BrandlRobert Patrick FingerIris Maria HeidMatthias Marten Mauschitz
Published in: Klinische Monatsblatter fur Augenheilkunde (2023)
Epidemiological studies on age-related macular degeneration (AMD) provide crucial data on the frequency of early and late forms as well as associated risk factors. The increasing number of population-based cross-sectional and longitudinal cohort studies in Germany and Europe with published data is making prevalence and incidence estimators for AMD more robust, although they show mostly method-related fluctuations. This review article brings together the latest published epidemiological measures for AMD from Germany and Central as well as Western Europe. Based on this data and population figures for Germany and Europe, prevalence is projected, and future trends are forecasted. The epidemiological evidence for AMD-associated risk factors is also improving, especially through meta-analyses within large consortia with correspondingly high case numbers. This review article summarizes the latest findings and resulting recommendations for prevention approaches. Additionally, it discusses treatment options and future challenges.
Keyphrases
  • age related macular degeneration
  • meta analyses
  • cross sectional
  • risk factors
  • electronic health record
  • big data
  • systematic review
  • current status
  • randomized controlled trial
  • south africa
  • clinical practice