Sex Differences in the Expression of the α5 Subunit of the GABAA Receptor in Alcoholics with and without Cirrhosis of the Liver.

Paulina JaneczekNatalie ColsonPeter R Dodd Joanne M Lewohl

Published in: Alcoholism, clinical and experimental research (2020)

There are sex differences in the expression of GABAA α5 and miR-203 in the brain of human alcoholics which are particularly marked in alcoholics with cirrhosis of the liver. Further, miR-203 may mediate the changes in expression of this GABAA receptor isoform that is brought about by alcohol exposure.

Keyphrases

poor prognosis
long non coding rna
cell proliferation
binding protein
endothelial cells
cerebral ischemia
pluripotent stem cells