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Efficacy and Safety of Ripretinib in Chinese Patients with Advanced Gastrointestinal Stromal Tumors as a Fourth- or Later-Line Therapy: A Multicenter, Single-Arm, Open-Label Phase II Study.

Jian LiShirong CaiYongjian ZhouJun ZhangYe ZhouHui CaoXin WuYanhong DengZhao HuangJuan DongLin Shen
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
The results demonstrated that ripretinib can clinically improve the outcomes of Chinese patients with advanced GIST as a fourth- or later-line therapy. The efficacy, safety, and PK profiles of ripretinib are consistent with those in the global patient population.
Keyphrases
  • phase ii study
  • open label
  • clinical trial
  • locally advanced
  • phase ii
  • case report
  • randomized controlled trial
  • phase iii
  • cross sectional
  • adipose tissue
  • mesenchymal stem cells
  • metabolic syndrome
  • smoking cessation