Randomised controlled trial to investigate the effectiveness of thoracic epidural and paravertebral blockade in reducing chronic post-thoracotomy pain (TOPIC): a pilot study to assess feasibility of a large multicentre trial.
Joyce YeungLee MiddletonKostas TryposkiadisAmy KerrJane DanielsBabu NaiduTeresa MelodyAndreas GoebelMatthew WilsonSajith KumarLajos SzentgyorgyiSarah FlanaganRajesh ShahAntony WorrallFang GaoPublished in: BMJ open (2019)
ISRCTN45041624.
Keyphrases
- study protocol
- randomized controlled trial
- spinal cord
- neuropathic pain
- thoracic surgery
- chronic pain
- clinical trial
- pain management
- open label
- systematic review
- postoperative pain
- ultrasound guided
- spinal cord injury
- aortic valve replacement
- phase iii
- phase ii
- placebo controlled
- heart failure
- cross sectional
- left ventricular
- transcatheter aortic valve replacement
- aortic stenosis