TRPP2 is located in the primary cilia of human non-pigmented ciliary epithelial cells.
Wenxu ZhengManuela SchmidtDaniela SuesskindBogomil VoykovSven SchnichelsPublished in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2023)
The expression of TRPP2 and the primary cilium in the CB may indicate a possible role, such as the sensing of hydrostatic pressure, for the regulation of IOP. Functional studies via patch clamp or pharmacological intervention have yet to clarify the relevance for the physiological situation or aqueous humor regulation.