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A distinct human CD4+ T cell subset that secretes CXCL13 in rheumatoid synovium.
Shio Kobayashi
Koichi Murata
Hideyuki Shibuya
Mami Morita
Masahiro Ishikawa
Moritoshi Furu
Hiromu Ito
Juichi Ito
Shuichi Matsuda
Takeshi Watanabe
Hiroyuki Yoshitomi
Published in:
Arthritis and rheumatism (2014)
CXCL13-producing CD4+ T cells induced in RA synovium may play a role in the recruitment of CXCR5+ cells, such as B cells and circulating follicular helper T cells, and in ectopic lymphoid neogenesis at sites of inflammation.
Keyphrases
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endothelial cells
induced apoptosis
high glucose
oxidative stress
diabetic rats
cell cycle arrest
rheumatoid arthritis
regulatory t cells
induced pluripotent stem cells
pluripotent stem cells
drug induced
ankylosing spondylitis
rheumatoid arthritis patients
cell death
cell proliferation
pi k akt
idiopathic pulmonary fibrosis