Effects and Safety of the Tripterygium Glycoside Adjuvant Methotrexate Therapy in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis.

Qi GengBin LiuYanfang MaHuizhen LiNannan ShiGuilin OuyangZhixing NieJianfeng Yi Yaolong Chen Yanping Wang Cheng Lu

Published in: Evidence-based complementary and alternative medicine : eCAM (2022)

TG adjuvant MTX therapy is more effective than MTX monotherapy and is a safe strategy for RA treatment in doses of 30 or 60 mg/day over a treatment course of six months. However, high-quality multicenter RCT studies with large sample sizes are still needed to confirm the effects and clinical safety of different courses and doses of TG adjuvant MTX therapy.

Keyphrases

rheumatoid arthritis
early stage
combination therapy
disease activity
randomized controlled trial
high dose
systemic lupus erythematosus
clinical trial
cell therapy
cross sectional
open label
mesenchymal stem cells