Chylomicrons Regulate Lacteal Permeability and Intestinal Lipid Absorption.
Georgia ZarkadaXun ChenXuetong ZhouMartin LangeLei ZengWenyu LvXuan ZhangYunhua LiWeibin ZhouKeli LiuDongying ChenNicolas RicardJames K LiaoYoung-Bum KimRui BeneditoLena Claesson-WelshKari AlitaloMichael SimonsRong JuXuri LiAnne EichmannFeng ZhangPublished in: Circulation research (2023)
Our results reveal that antagonistic inputs into ROCK-dependent cytoskeleton contractions regulate the interconversion of lymphatic junctions in the intestine and in other tissues, providing a tunable mechanism to control the lymphatic barrier.