Michael Simons

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 36

Top Venues

Circulation research

Nature communications

Science advances

Proceedings of the National Academy of Sciences of the United States of America

Yale University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Yale University

United States

RW Berliner Professor :: Medicine

Dartmouth College Geisel School of Medicine

United States

AG Huber Professor :: Medicine

Beth Israel Deaconess Medical Center

United States

Associate Professor :: Medicine

Beth Israel Deaconess Medical Center

United States

Assisatnt Professor :: Medicine

Publications

Shalil Khanal, Yuanhang Liu, Adebowale O Bamidele, Alexander Q Wixom, Alexander M Washington, Nidhi Jalan Sakrikar, Shawna A Cooper, Ivan Vuckovic, Song Zhang, Jun Zhong, Kenneth L Johnson, M Cristine Charlesworth, Iljung Kim, Yubin Yeon, Sangwoong Yoon, Yung-Kyun Noh, Chady Meroueh, Abdul Aziz Timbilla, Usman Yaqoob, Jinhang Gao, Yo Han Kim, Fabrice Lucien, Robert C Huebert, Nissim Hay, Michael Simons, Vijay H Shah, Enis Kostallari
Glycolysis in hepatic stellate cells coordinates fibrogenic extracellular vesicle release spatially to amplify liver fibrosis. Science advances 10 (26) (2024)
Ruizhe Ren, Sha Ding, Kefan Ma, Yuanqing Jiang, Yiran Wang, Junbo Chen, Yunyun Wang, Yaohui Kou, Xiao Fan, Xiaolong Zhu, Lingfeng Qin, Cong Qiu, Michael Simons, Xiyang Wei, Luyang Yu
SUMOylation Fine-Tunes Endothelial HEY1 in the Regulation of Angiogenesis. Circulation research 134 (2) (2024)
Ruizhe Ren, Sha Ding, Kefan Ma, Yuanqing Jiang, Yiran Wang, Junbo Chen, Yunyun Wang, Yaohui Kou, Xiao Fan, Xiaolong Zhu, Lingfeng Qin, Cong Qiu, Michael Simons, Xiyang Wei, Luyang Yu
SUMOylation Fine-Tunes Endothelial HEY1 in the Regulation of Angiogenesis. Circulation research 134 (2) (2024)
Shalil Khanal, Yuanhang Liu, Adebowale O Bamidele, Alexander Q Wixom, Alexander M Washington, Nidhi Jalan Sakrikar, Shawna A Cooper, Ivan Vuckovic, Song Zhang, Jun Zhong, Kenneth L Johnson, M Cristine Charlesworth, Iljung Kim, Yubin Yeon, Sangwoong Yoon, Yung-Kyun Noh, Chady Meroueh, Abdul Aziz Timbilla, Usman Yaqoob, Jinhang Gao, Yo Han Kim, Fabrice Lucien, Robert C Huebert, Nissim Hay, Michael Simons, Vijay H Shah, Enis Kostallari
Glycolysis in hepatic stellate cells coordinates fibrogenic extracellular vesicle release spatially to amplify liver fibrosis. Science advances 10 (26) (2024)
Ruizhe Ren, Sha Ding, Kefan Ma, Yuanqing Jiang, Yiran Wang, Junbo Chen, Yunyun Wang, Yaohui Kou, Xiao Fan, Xiaolong Zhu, Lingfeng Qin, Cong Qiu, Michael Simons, Xiyang Wei, Luyang Yu
SUMOylation Fine-Tunes Endothelial HEY1 in the Regulation of Angiogenesis. Circulation research 134 (2) (2024)
Ruizhe Ren, Sha Ding, Kefan Ma, Yuanqing Jiang, Yiran Wang, Junbo Chen, Yunyun Wang, Yaohui Kou, Xiao Fan, Xiaolong Zhu, Lingfeng Qin, Cong Qiu, Michael Simons, Xiyang Wei, Luyang Yu
SUMOylation Fine-Tunes Endothelial HEY1 in the Regulation of Angiogenesis. Circulation research 134 (2) (2024)
Ruizhe Ren, Sha Ding, Kefan Ma, Yuanqing Jiang, Yiran Wang, Junbo Chen, Yunyun Wang, Yaohui Kou, Xiao Fan, Xiaolong Zhu, Lingfeng Qin, Cong Qiu, Michael Simons, Xiyang Wei, Luyang Yu
SUMOylation Fine-Tunes Endothelial HEY1 in the Regulation of Angiogenesis. Circulation research (2024)
Ruizhe Ren, Sha Ding, Kefan Ma, Yuanqing Jiang, Yiran Wang, Junbo Chen, Yunyun Wang, Yaohui Kou, Xiao Fan, Xiaolong Zhu, Lingfeng Qin, Cong Qiu, Michael Simons, Xiyang Wei, Luyang Yu
SUMOylation Fine-Tunes Endothelial HEY1 in the Regulation of Angiogenesis. Circulation research 134 (2) (2024)
Shalil Khanal, Yuanhang Liu, Adebowale O Bamidele, Alexander Q Wixom, Alexander M Washington, Nidhi Jalan Sakrikar, Shawna A Cooper, Ivan Vuckovic, Song Zhang, Jun Zhong, Kenneth L Johnson, M Cristine Charlesworth, Iljung Kim, Yubin Yeon, Sangwoong Yoon, Yung-Kyun Noh, Chady Meroueh, Abdul Aziz Timbilla, Usman Yaqoob, Jinhang Gao, Yo Han Kim, Fabrice Lucien, Robert C Huebert, Nissim Hay, Michael Simons, Vijay H Shah, Enis Kostallari
Glycolysis in hepatic stellate cells coordinates fibrogenic extracellular vesicle release spatially to amplify liver fibrosis. Science advances 10 (26) (2024)
Ruizhe Ren, Sha Ding, Kefan Ma, Yuanqing Jiang, Yiran Wang, Junbo Chen, Yunyun Wang, Yaohui Kou, Xiao Fan, Xiaolong Zhu, Lingfeng Qin, Cong Qiu, Michael Simons, Xiyang Wei, Luyang Yu
SUMOylation Fine-Tunes Endothelial HEY1 in the Regulation of Angiogenesis. Circulation research 134 (2) (2024)
Nabil E Boutagy, Joseph W Fowler, Kariona A Grabińska, Rebecca Cardone, Qiushi Sun, Kyla R Vazquez, Michael B Whalen, Xiaolong Zhu, Raja Chakraborty, Kathleen A Martin, Michael Simons, Casey E Romanoski, Richard G Kibbey, William C Sessa
TNFα increases the degradation of pyruvate dehydrogenase kinase 4 by the Lon protease to support proinflammatory genes. Proceedings of the National Academy of Sciences of the United States of America 120 (38) (2023)
Xiaofei Zhou, Yuanqing Jiang, Yuewen Wang, Linge Fan, Yunhui Zhu, Yefeng Chen, Yiran Wang, Yingyi Zhu, Hongkun Wang, Zihang Pan, Zhoubin Li, Xiaolong Zhu, Ruizhe Ren, Zhen Ge, Dongwu Lai, En-Yin Lai, Ting Chen, Kai Wang, Ping Liang, Lingfeng Qin, Cuiqing Liu, Cong Qiu, Michael Simons, Luyang Yu
Endothelial FIS1 DeSUMOylation Protects Against Hypoxic Pulmonary Hypertension. Circulation research (2023)
Georgia Zarkada, Xun Chen, Xuetong Zhou, Martin Lange, Lei Zeng, Wenyu Lv, Xuan Zhang, Yunhua Li, Weibin Zhou, Keli Liu, Dongying Chen, Nicolas Ricard, James K Liao, Young-Bum Kim, Rui Benedito, Lena Claesson-Welsh, Kari Alitalo, Michael Simons, Rong Ju, Xuri Li, Anne Eichmann, Feng Zhang
Chylomicrons Regulate Lacteal Permeability and Intestinal Lipid Absorption. Circulation research (2023)
Menno P J de Winther, Magnus Bäck, Paul C Evans, Delphine Gomez, Isabel Goncalves, Helle F Jørgensen, Rory R Koenen, Esther Lutgens, Giuseppe Danilo Norata, Elena Osto, Lea Dib, Michael Simons, Konstantinos Stellos, Suo Ctc Bladder Committee, Holger Winkels, Marie-Luce Bochaton-Piallat, Claudia Monaco
Translational opportunities of single-cell biology in atherosclerosis. European heart journal (2022)
Celine Souilhol, Blanca Tardajos Ayllon, Xiuying Li, Mannekomba R Diagbouga, Ziqi Zhou, Lindsay Canham, Hannah Roddie, Daniela Pirri, Emily V Chambers, Mark J Dunning, Mark Ariaans, Jin Li, Yun Fang, Helle F Jørgensen, Michael Simons, Rob Krams, Johannes Waltenberger, Maria Fragiadaki, Victoria Ridger, Sarah De Val, Sheila E Francis, Timothy Ja Chico, Jovana Serbanovic-Canic, Paul C Evans
JAG1-NOTCH4 mechanosensing drives atherosclerosis. Science advances 8 (35) (2022)
Heon-Woo Lee, Yanying Xu, Xiaolong Zhu, Cholsoon Jang, Woosoung Choi, Hosung Bae, Weiwei Wang, Liqun He, Suk-Won Jin, Zoltan Arany, Michael Simons
Endothelium-derived lactate is required for pericyte function and blood-brain barrier maintenance. The EMBO journal 41 (9) (2022)
Xiaolong Zhu, Cong Qiu, Yiran Wang, Yuanqing Jiang, Yefeng Chen, Linge Fan, Ruizhe Ren, Yunyun Wang, Yu Chen, Yanzhi Feng, Xiaofei Zhou, Yunhui Zhu, Zhen Ge, Dongwu Lai, Lingfeng Qin, Michael Simons, Luyang Yu
FGFR1 SUMOylation coordinates endothelial angiogenic signaling in angiogenesis. Proceedings of the National Academy of Sciences of the United States of America 119 (26) (2022)
Hanqiang Deng, Yanying Xu, Xiaoyue Hu, Zhen W Zhuang, Yuzhou Chang, Yewei Wang, Aglaia Ntokou, Martin Alexander Schwartz, Bing Su, Michael Simons
MEKK3-TGFβ crosstalk regulates inward arterial remodeling. Proceedings of the National Academy of Sciences of the United States of America 118 (51) (2022)
Dongying Chen, Michael Simons
Emerging roles of PLCγ1 in endothelial biology. Science signaling 14 (694) (2021)
Nicolas Ricard, Sabine Bailly, Christophe Guignabert, Michael Simons
The quiescent endothelium: signalling pathways regulating organ-specific endothelial normalcy. Nature reviews. Cardiology 18 (8) (2021)
Heon-Woo Lee, Yanying Xu, Liqun He, Woosoung Choi, David G Gonzalez, Suk-Won Jin, Michael Simons
Role of Venous Endothelial Cells in Developmental and Pathologic Angiogenesis. Circulation 144 (16) (2021)
Hanqiang Deng, Elizabeth Min, Nicolas Baeyens, Brian G Coon, Rui Hu, Zhen W Zhuang, Minghao Chen, Billy Huang, Titilayo Afolabi, Georgia Zarkada, Angela Acheampong, Kathleen McEntee, Anne Eichmann, Fang Liu, Bing Su, Michael Simons, Martin Alexander Schwartz
Activation of Smad2/3 signaling by low fluid shear stress mediates artery inward remodeling. Proceedings of the National Academy of Sciences of the United States of America 118 (37) (2021)
Emma Ristori, Vittoria Cicaloni, Laura Salvini, Laura Tinti, Cristina Tinti, Michael Simons, Federico Corti, Sandra Donnini, Marina Ziche
Amyloid-β Precursor Protein APP Down-Regulation Alters Actin Cytoskeleton-Interacting Proteins in Endothelial Cells. Cells 9 (11) (2020)
Pei-Yu Chen, Lingfeng Qin, Guangxin Li, Zheng Wang, James E Dahlman, Jose Malagon-Lopez, Sharvari Gujja, Nicholas A Cilfone, Kevin J Kauffman, Lele Sun, Hongye Sun, Xinbo Zhang, Binod Aryal, Alberto Canfran-Duque, Rebecca Liu, Pascal Kusters, Alfica Sehgal, Yang Jiao, Daniel G Anderson, Jeffrey Gulcher, Carlos Fernández-Hernando, Esther Lutgens, Martin A Schwartz, Jordan S Pober, Thomas W Chittenden, George Tellides, Michael Simons
Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis. Nature metabolism 1 (9) (2019)
Federico Corti, Yingdi Wang, John M Rhodes, Deepak Atri, Stephanie Archer-Hartmann, Jiasheng Zhang, Zhen W Zhuang, Dongying Chen, Tianyun Wang, Zhirui Wang, Parastoo Azadi, Michael Simons
Publisher Correction: N-terminal syndecan-2 domain selectively enhances 6-O heparan sulfate chains sulfation and promotes VEGFA165-dependent neovascularization. Nature communications 10 (1) (2019)
Federico Corti, Yingdi Wang, John M Rhodes, Deepak Atri, Stephanie Archer-Hartmann, Jiasheng Zhang, Zhen W Zhuang, Dongying Chen, Tianyun Wang, Zhirui Wang, Parastoo Azadi, Michael Simons
N-terminal syndecan-2 domain selectively enhances 6-O heparan sulfate chains sulfation and promotes VEGFA165-dependent neovascularization. Nature communications 10 (1) (2019)
Nicolas Ricard, Rizaldy P Scott, Carmen J Booth, Heino Velazquez, Nicholas A Cilfone, Javier L Baylon, Jeffrey R Gulcher, Susan E Quaggin, Thomas W Chittenden, Michael Simons
Endothelial ERK1/2 signaling maintains integrity of the quiescent endothelium. The Journal of experimental medicine 216 (8) (2019)
Huanjiao Jenny Zhou, Zhe Xu, Zongren Wang, Haifeng Zhang, Zhen W Zhuang, Michael Simons, Wang Min
Author Correction: SUMOylation of VEGFR2 regulates its intracellular trafficking and pathological angiogenesis. Nature communications 10 (1) (2019)
Nicolas Ricard, Jiasheng Zhang, Zhen W Zhuang, Michael Simons
Isoform-Specific Roles of ERK1 and ERK2 in Arteriogenesis. Cells 9 (1) (2019)
Feng Zhang, Georgia Zarkada, Jinah Han, Jinyu Li, Alexandre Dubrac, Roxana Ola, Gael Genet, Kevin Boyé, Pauline Michon, Steffen E Künzel, Joao Paulo Camporez, Abhishek K Singh, Guo-Hua Fong, Michael Simons, Patrick Tso, Carlos Fernández-Hernando, Gerald I Shulman, William C Sessa, Anne Eichmann
Lacteal junction zippering protects against diet-induced obesity. Science (New York, N.Y.) 361 (6402) (2018)
Heon-Woo Lee, Pengchun Yu, Michael Simons
Recent advances in understanding lymphangiogenesis and metabolism. F1000Research 7 (2018)
Huanjiao Jenny Zhou, Zhe Xu, Zongren Wang, Haifeng Zhang, Zhen W Zhuang, Michael Simons, Wang Min
SUMOylation of VEGFR2 regulates its intracellular trafficking and pathological angiogenesis. Nature communications 9 (1) (2018)
Katja Burk, Erik Mire, Anaïs Bellon, Mélanie Hocine, Jeremy Guillot, Filipa Moraes, Yutaka Yoshida, Michael Simons, Sophie Chauvet, Fanny Mann
Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits. Nature communications 8 (2017)
Elisabetta Dejana, Karen K Hirschi, Michael Simons
The molecular basis of endothelial cell plasticity. Nature communications 8 (2017)
Yingdi Wang, Nicolas Baeyens, Federico Corti, Keiichiro Tanaka, Jennifer S Fang, Jiasheng Zhang, Yu Jin, Brian Coon, Karen K Hirschi, Martin A Schwartz, Michael Simons
Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development. Development (Cambridge, England) 143 (23) (2016)
Pei-Yu Chen, Lingfeng Qin, Guangxin Li, George Tellides, Michael Simons
Smooth muscle FGF/TGFβ cross talk regulates atherosclerosis progression. EMBO molecular medicine 8 (7) (2016)

Michael Simons.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Michael Simons