Telomere Length and Mitochondrial DNA Copy Number Variations in Patients with Obesity: Effect of Diet-Induced Weight Loss-A Pilot Study.
Raffaella CancelloFederica ReyStephana CarelliStefania CattaldoJacopo Maria FontanaIlaria GoitreValentina PonzoFabio Dario MerloGian Vincenzo ZuccottiSimona BertoliPaolo CapodaglioSimona BoAmelia BrunaniPublished in: Nutrients (2022)
TL and the mtDNA copy number significantly increased in patients with obesity and with lower baseline TL values after a 1-year lifestyle intervention. Larger longitudinal studies are needed to confirm the results of this pilot study.
Keyphrases
- copy number
- weight loss
- mitochondrial dna
- bariatric surgery
- roux en y gastric bypass
- metabolic syndrome
- gastric bypass
- genome wide
- insulin resistance
- weight gain
- randomized controlled trial
- dna methylation
- high fat diet induced
- type diabetes
- glycemic control
- obese patients
- cross sectional
- gene expression
- physical activity
- skeletal muscle
- case control
- body mass index