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Molecular cloning and characterization of NPC1L1 in the Chinese tree shrew (Tupaia belangeri chinensis).

Xiuying KuiDandan QiuWenguang WangNa LiPinfen TongXiaomei SunLiangzi JinWei DengJiejie DaiCaixia Lu
Published in: Molecular biology reports (2021)
The homology of tree shrew NPC1L1 was closer to human than that of rodent NPC1L1. The expression of tsNPC1L1 was the highest in small intestine, and was detectable in lung and pancreas. These results may be useful in the study of tsNPC1L1 function in cholesterol absorption and HCV infection.
Keyphrases
  • endothelial cells
  • poor prognosis
  • hepatitis c virus
  • induced pluripotent stem cells
  • human immunodeficiency virus
  • binding protein
  • pluripotent stem cells
  • single molecule