Urine inter-alpha-trypsin inhibitor family-related proteins may serve as biomarkers for disease activity of lupus.
Jun JiangJin ZhaoYuhua WangDan LiuMan ZhangPublished in: Journal of clinical laboratory analysis (2022)
In this exploratory study, we evaluated the expression of ITI family-related proteins in the urine of SLE and found that urine ITIH2 and ECM1 were closely related to SLE activity, especially kidney damage, providing an experimental basis for further exploration of the potential roles in monitoring lupus and lupus nephritis activity.