Clinical effectiveness of tigecycline in combination therapy against nosocomial pneumonia caused by CR-GNB in intensive care units: a retrospective multi-centre observational study.
Kuang-Yao YangChung-Kan PengChau-Chyun SheuYu-Chao LinMing-Cheng ChanSheng-Huei WangChia-Min ChenChih-Yu ChenZhe-Rong ZhengJia-Yih Fengnull nullPublished in: Journal of intensive care (2023)
In this retrospective observational study that included ICU-admitted patients with nosocomial pneumonia caused by tigecycline-susceptible CR-GNB, mostly CRAB, tigecycline as part of a combination treatment regimen was associated with lower clinical failure and all-cause mortality rates.
Keyphrases
- acinetobacter baumannii
- combination therapy
- klebsiella pneumoniae
- intensive care unit
- multidrug resistant
- drug resistant
- pseudomonas aeruginosa
- randomized controlled trial
- systematic review
- mechanical ventilation
- escherichia coli
- cross sectional
- methicillin resistant staphylococcus aureus
- cystic fibrosis
- respiratory failure
- replacement therapy