Methylation of DIRAS1 promotes colorectal cancer progression and may serve as a marker for poor prognosis.

Ruipan ZhengDan GaoTao HeMeiying ZhangXiaomei ZhangEnqiang LinghuLixin WeiMingzhou Guo

Published in: Clinical epigenetics (2017)

DIRAS1 is frequently methylated in human colorectal cancer and the expression of DIRAS1 is regulated by promoter region methylation. Methylation of DIRAS1 is a marker of poor prognosis in human colorectal cancer.

Keyphrases

poor prognosis
long non coding rna
dna methylation
endothelial cells
genome wide
gene expression
pluripotent stem cells
transcription factor
binding protein