Methylation of DIRAS1 promotes colorectal cancer progression and may serve as a marker for poor prognosis.
Ruipan ZhengDan GaoTao HeMeiying ZhangXiaomei ZhangEnqiang LinghuLixin WeiMingzhou GuoPublished in: Clinical epigenetics (2017)
DIRAS1 is frequently methylated in human colorectal cancer and the expression of DIRAS1 is regulated by promoter region methylation. Methylation of DIRAS1 is a marker of poor prognosis in human colorectal cancer.