An expert consensus to standardise the assessment of histological disease activity in Crohn's disease clinical trials.

Ahmed AlmradiChristopher MaGeert R D'HaensWilliam J Sandborn Claire E ParkerLeonardo GuizzettiPaula Borralho NunesGert De HertoghRoger M FeakinsReena KhannaGregory Y LauwersAart MookhoekReetesh K PaiLaurent Peyrin BirouletRobert RiddellChristophe RostyDavid F SchaefferMark A ValasekSiddharth SinghEileen CrowleyBrian G Feagan Vipul Jairath Rish K Pai

Published in: Alimentary pharmacology & therapeutics (2021)

We evaluated the appropriateness of items for assessing histological disease activity in CD clinical trials. These items will be used to develop a novel histological index.

Keyphrases

disease activity
clinical trial
systemic lupus erythematosus
rheumatoid arthritis
rheumatoid arthritis patients
ankylosing spondylitis
juvenile idiopathic arthritis
phase ii
randomized controlled trial
open label
phase iii
study protocol
double blind
clinical evaluation